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2 rezultati
Nicotine-induced morphological changes in rat aorta: the protective role of melatonin.
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We analyzed the morphological changes in rat aortas during nicotine administration in order to investigate the involvement of vascular smooth muscle cells (VSMCs) in the regulation of vascular wall homeostasis. We also considered the possibility of restoring VSMC changes using melatonin as an
Novel role of Egr-1 in nicotine-related neointimal formation.
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OBJECTIVE
The aim of this study was to investigate the mechanisms by which nicotine increases vascular smooth muscle cell (VSMC) proliferation and post-injury neointimal formation.
RESULTS
Vascular injury was inflicted in the right iliac artery of nicotine-treated and control rats. Nicotine
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