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Page 1 od 68 rezultati
Effect of L-ornithine 8-vasopressin on blood loss during liposuction.
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In this comparative study, we carried out liposuction on 20 patients randomly divided in two groups to find an alternative medication to epinephrine that would not result in secondary effects at the cardiovascular level but would offer a similar vasoconstricting capacity. Also, a variation of the
Impact of ornithine phenylacetate (OCR-002) in lowering plasma ammonia after upper gastrointestinal bleeding in cirrhotic patients.
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BACKGROUND
Ornithine phenylacetate (OP) has been proven effective in lowering ammonia plasma levels in animals, and to be well tolerated in cirrhotic patients. A trial to assess OP efficacy in lowering plasma ammonia levels versus placebo in cirrhotic patients after an upper gastrointestinal
Ornithine transcarbamylase deficiency unmasked because of gastrointestinal bleeding.
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Ornithine transcarbamylase (OTC) is a mitochondrial-matrix enzyme that catalyzes conversion of ornithine and carbamyl phosphate to citrulline, the second step in the urea cycle. The urea cycle is the most important pathway to detoxification of ammonia in human beings. Ornithine transcarbamylase
Intracranial haemorrhage in siblings and ornithine transcarbamylase deficiency.
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[Ornithine carbamoyltransferase activity in experimental hemorrhagic shock in dogs].
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Ornithine carbamoyl transferase as an index of severity in hemorrhagic shock.
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[Influence of ornithine 8-vasopressin preparation upon blood loss after induced abortions performed under local anesthesia].
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Postoperative changes of ornithine carbamoyl transferase activity in serum (S-OCT) in relation to blood loss during operations in man.
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Inhibition of ornithine aminotransferase by 5-fluoromethylornithine: protection against acute thioacetamide intoxication by elevated tissue ornithine levels.
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5-Fluoromethylornithine (5FMOrn) is a selective inactivator of ornithine aminotransferase. Its administration causes a dramatic increase of ornithine concentrations in all tissues. Treatment of mice with 20 mg.kg-1 5FMOrn shortly before or after a lethal dose (600 mg.kg-1, intraperitoneally) of
[Hyperammonemia in the newborn through ornithine transcarbamylase deficiency (author's transl)].
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This is a report of a family with hyperammonemia in the newborn, very probably due to ornithine transcarbamylase deficiency. Typically the male infant died in the newborn period within 74 hours. In the female newborn it was possible to provide a normal development with protein restricted diet. In
Gyrate atrophy of choroid and retina complicated by vitreous hemorrhage.
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We describe two patients with gyrate atrophy of the choroid and retina who suffered from vitreous hemorrhages in adolescence. The diagnosis of gyrate atrophy was confirmed biochemically and clinically; hyperornithinemia and a deficiency of ornithine ketoacid transaminase were confirmed
A novel nitric oxide scavenger decreases liver injury and improves survival after hemorrhagic shock.
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We tested the ability of a nitric oxide (NO) scavenger to reduce tissue injury in a rodent model of hemorrhagic shock. Rats were hemorrhaged to a mean arterial blood pressure (MAP) of 40 mmHg and then resuscitated when either 30% of their shed blood had been returned (group 1) or after 100 min of
The modulation of hepatic injury and heat shock expression by inhibition of inducible nitric oxide synthase after hemorrhagic shock.
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The role of nitric oxide (NO) in maintaining homeostasis and regulating organ function during hemorrhagic shock is complex. The inducible NO synthase (iNOS) has been hypothesized to play a critical role in the pathophysiologic consequences of severe hemorrhage. Heat shock protein (HSP) expression is
Effect of selective inhibitors of nitric oxide synthesis on the course of experimental hemorrhagic shock.
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Selective inhibitors of NO synthesis (derivatives of lysine, ornithine, and isothiourea) increased the efficiency of infusion therapy for experimental hemorrhagic shock in rats. These changes were related to improvement of cardiac function (increase in stroke volume, cardiac output, and left
Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses.
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OBJECTIVE
To explore the hypothesis that the survival benefit of mild, therapeutic hypothermia during hemorrhagic shock is associated with inhibition of lipid peroxidation and the acute inflammatory response.
METHODS
Prospective and randomized.
METHODS
Animal research facility.
METHODS
Male
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