osteoporosis/seizures

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Methylenetetrahydrofolate Reductase Deficiency in Ischemic Stroke

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Epileptic seizures that begin in adulthood seriously affect patients, their relatives and the society in which they live financially and psychologically. The etiology of epileptic seizures starting at adult age includes head trauma, central nervous system infections, intracranial lesions,

The PORTRAIT Study

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Hypophosphatasia (HPP) is caused by mutations in the tissue non-specific alkaline phosphatase (TNSALP) gene with deficiency in TNSALP activity. This leads to accumulation of inorganic pyrophosphate, a potent inhibitor of bone mineralization, which causes rickets and osteomalacia, and of pyridoxal

Treatment of Vitamin D Deficiency With Large Bolus Cholecalciferol

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Study is looking at patients with diagnosed vitamin D deficiency (<20ng/mL). Participants are healthy adults between 18 and 75. No diagnosis of cancer, pregnancy, hypercalcemia, hyperparathyroidism, gastrointestinal absorption disorder, or chronic kidney disease and not taking medications for

non_invasive_aICP_Tumor

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Primary brain tumors in adults are less common than metastatic tumors. The most frequent are glioblastoma multiforme, metastases, anaplastic astrocytoma, meningioma, pituitary tumors and vestibular schwannoma. 70% of the tumors in adults are supratentorial. The most infratentorial tumors are

Health Burden of Hypophosphatasia

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This is an observational retrospective study to describe the clinical problems and healthcare use of adults and children with hypophosphatasia. Interviews will be conducted with patients with childhood- and adult-onset hypophosphatasia (and the parents of the children). Hospital notes, appointment

Characterization of Neuropsychologic and Physical Performance in Geriatric Patients With Hyponatremia.

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With an occurrence of up to 30%, hyponatremia, defined as a serum sodium concentration of less than 135 mmol/L, is the most commonly encountered electrolyte disorder in hospitalized patients today. The highest incidence of hyponatremia is found in the elderly. Retrospective analyses clearly show an

Antiepileptic Drugs and Osteoporotic Prevention Trial

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The study is planned to last two years. You will be required to make a total of 6 visits to the clinic during this two year study period. At the first visit, 12 months and, approximately 24 months, you will have a bone mineral density test (BMD) of your hip and spine. A BMD is similar to having an

The Winchester Falls Project

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BACKGROUND INFORMATION At least one in three people aged sixty five and over are reported to fall in the community each year and in the very elderly this figure is nearer 40 % (1,2). The morbidity and mortality resulting from falls in the elderly is substantial and the costs associated with such

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