patients without pancreatic adenocarcinoma

Carcinoma

Pancreatic Ductal

Adipose tissue sampling during surgery and urine sampling

Damien JOLLY

Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma

Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma : a Case Control Study.

QuEChERS method to extract organochlorines Use of Agilent 7010 Detection limit : 10ng/g of adipose tissue

Use of Agilent 7010 Detection limit : 0.1microg/L

CHU de Reims

Patients with pancreatic cancer and age&sex-matched controls without any cancer from a distinct population area (district of Stockholm). Patients with pancreatic cancer will be subjected to pancreatic surgery

Germline DNA and tumour DNA (PDAC patients). Saliva and urine (DNA).

Pancreatic Cancer

Surgical removal of the pancreatic tumour (cancer) in the intervention group

Pancreatic Surgery

Karolinska University Hospital, Gastrocentrum

Clinical Trial of Pancreatic Cancer in Stockholm.

Prospective Populationbased Study on Pancreatic Cancer in Stockholm- Mutation Profiling Characteristics, Biobanking and Risk Factors.

Matthias Löhr

Professor

Karolinska University Hospital

Pancreatic Insufficiency

The Emory Clinic

Pancreatic Insufficiency Secondary to Tobacco Exposure

The primary outcome is presence or absence of pancreatic insufficiency as determined by fecal elastase-1 measurement

Field Willingham MD

Director of Endoscopy

Emory University

Group of patients with diagnosis of NSCLC and exposure to tabacco smoking

Patients whit diagnosis of NSCLC and exposure to wood smoke

Patients whit diagnosis of NSCLC and exposure to tabacco smoking and wood smoke

Patients whit diagnosis of NSCLC and whitout exposure to risk factor

The tumor samples, both formalin-fixed or paraffin-embedded, used for the histological diagnosis of patients will be obtained from the Pathology Departments of the National Cancer Institute and the National Institute of Respiratory Diseases; these samples will be used to gather DNA for the analysis of K-RAS mutations. The clinical data of the patients will be obtained from their medical files.

Non-Small Cell Lung Cancer

Instituto Nacional de Cancerología

K-RAS Oncogene Mutation in Patients With Advanced Non-Small Cell Lung Cancer Associated With Exposure to Wood Smoke and Tobacco Smoking: Therapeutic Implications

Tumor specimens were collected at the time of diagnosis. WSE was defined as being exposed to fumes resulting from burning wood in fireplaces and wood stoves for >5 years for at least 4 hours per day. The WSE index was calculated by multiplying the number of daily hours exposed by the number of years' exposure. A non-smoker was defined as being someone having a lifetime exposure of less than 100 cigarettes; the tobacco smoking index was calculated by multiplying the number of cigarette packs consumed per day by the number of years spent smoking.

EGFR (exon 18-21) and KRAS gene mutations from some samples were detected by Therascreen RGQ PCR Kit (QUIAGEN, Scorpions ARMS method), according to the manufacturer's instructions from the four arms.

pancreatic neoplasms/nikotin

Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma

Clinical Trial of Pancreatic Cancer in Stockholm.

Pancreatic Insufficiency Secondary to Tobacco Exposure

K-RAS Oncogene Mutation in Patients With Advanced Non-Small Cell Lung Cancer Associated With Exposure to Wood Smoke and Tobacco Smoking: Therapeutic Implications

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