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prostaglandin f 2 alpha/upala
Veza se sprema u međuspremnik
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Prospective Breast Cancer Biobanking
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A. Early detection of systemic relapses in breast cancer.
WP 1. Analysis of primary tumor.
Analysis of primary tumor and metastases (Pathology group). In this work package both DNA and RNA from the primary tumors of 125 high-risk (Luminal-B) patients will be analyzed by next-generation sequencing
Topical Cetirizine in Androgenetic Alopecia in Females
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Androgenetic alopecia (AGA) is the most common form of alopecia in men and women. It is a hereditary, androgen-dependent, progressive thinning of scalp hair that follows a defined pattern. The disease mechanism is still relatively poorly understood, but involves a strong genetic contribution as well
Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block
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Postoperative pain is one of the main causes of respiratory function derangement after abdominal surgery .Transversus abdominis plane (TAP) block is widely used in abdominal surgery for postoperative analgesia The transversus abdominis plane (TAP) block is aperipheral nerve block that involves the
Comparison of Short and Standard Dental Implants
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INTRODUCTION
Dental implants are usually considered an alternative treatment option to replace lost teeth in edentulous patients. The rate of implant placement in regions more difficult to rehabilitate has increased with the increase in the success of osseointegration and survival. However, besides
Pathways of Eicosanoid Metabolism
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The objective of this study is to determine whether PGD2 is metabolized to 11-dehydro-TxB2 in humans. Because the levels of PGD2 and its metabolite, PGD-M, are low in human urine, the investigators will use the model of niacin-induced flushing which is associated with a increased release of PGD2
Intra-articular Oxygen-ozone Therapy for the Treatment of Knee Osteoarthritis Compared With Hyaluronic Acid
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Osteoarthritis is a degenerative condition that causes pain, impaired function and affects daily activities. In knee osteoarthritis, there is destruction of cartilage and subchondral bone, with the consequent narrowing of articular space. Besides the biomechanical factors, trauma and obesity; it is
A Randomized Open-labeled Study for Comparing Methods of Using Imrecoxib to Treat AS
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Ankylosing spondylitis (AS) is a chronic systemic inflammatory arthritis of unknown etiology, occurring in young men aged 16-25 and presenting the genetic predisposition. AS is a common rheumatic disease, with a prevalence of 0.3 ~ 0.5% in general people of China, which means that about 5 million
Meteorin-like Levels in Individuals With Periodontitis
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Periodontitis is a destructive chronic inflammatory disease that can start with localized inflammatory reactions created by the supporting tissues surrounding the teeth against microorganisms and then result in loss of teeth. Cytokines play an important role in inflammation that occurs in
Plasma Exchange in Patients With COVID-19 Disease and Invasive Mechanical Ventilation: a Randomized Controlled Trial
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Plasma exchange (PE) is a standardized and safe therapeutic procedure, used in the treatment of various diseases that require rapid and prolonged elimination of endogenous and exogenous substances, with deleterious effects on the function of different organs and systems. The efficacy and safety of
Protective Effect of Aspirin on COVID-19 Patients
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1. COVID-19 has a high infection rate and mortality, and serious complications such as heart injury cannot be ignored.
At present, the scale and harm of COVID 19 (Novel coronavirus pneumonia (NCP) has far surpassed that of SARS in 2003, with more than 80,000 cases confirmed in China and 3,119 deaths
The Copenhagen Analgesic Study
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Fetal gonadal development is essential for adult reproductive health. Experimental studies strongly suggest that maternal use of mild analgesics (e.g. paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs)) during pregnancy affect fetal gonadal development with possible severe reproductive
Defibrotide in COVID-19 Pneumonia
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As of March 12, 2020, coronavirus disease 2019 (COVID-19) has been confirmed in 125 048 people worldwide, carrying a mortality of approximately 3·7%, 1 compared with a mortality rate of less than 1% from influenza. There is an urgent need for effective treatment. The 2019 novel Coronavirus
Ketorolac Irrigant on Post Operative Pain
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When the treatment itself appears to initiate the onset of pain and/or swelling, the result can be very distressing to both the patient and the operator.
Patients might even consider postoperative pain and flare-up as a benchmark against which the clinician's skills are measured. Prevalence of
Pharmacokinetic and Tolerance Study of Meloxicam Eye Drops in Healthy Volunteers
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Meloxicam eye drops is a new class 2 drug of the country. The main ingredients are meloxicam. The other ingredients are hydroxypropyl-β-cyclodextrin, sodium hydroxide, boric acid, sodium chloride and water for injection. Among them, hydroxypropyl-β-cyclodextrin can increase the solubility of
Norepinephrine Infusion During Cardiopulmonary Bypass
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Rationale
1.1. Vasoplegia and cardiac surgery:
Vasoplegia Syndrome (VS), prevailing in about 20% of cardiac surgical procedures (1), is defined as low mean arterial pressure (MAP) with normal or high cardiac indices and which is resistant to treatment with the commonly used vasopressors. (2,3)
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