Tobacco Craving and Triggers in Persons With Schizophrenia
Paraules clau
Resum
Dates
Darrera verificació: | 08/31/2019 |
Primer enviat: | 04/01/2013 |
Inscripció estimada enviada: | 04/29/2013 |
Publicat per primera vegada: | 05/02/2013 |
Última actualització enviada: | 09/22/2019 |
Publicació de l'última actualització: | 09/24/2019 |
Data d'inici de l'estudi real: | 08/31/2013 |
Data estimada de finalització primària: | 05/31/2016 |
Data estimada de finalització de l’estudi: | 06/29/2017 |
Condició o malaltia
Fase
Criteris d'elegibilitat
Edats elegibles per estudiar | 18 Years Per a 18 Years |
Sexes elegibles per estudiar | All |
Mètode de mostreig | Probability Sample |
Accepta voluntaris saludables | Sí |
Criteris | Inclusion criteria 1. 18-55 year old males and females 2. currently smokes at least 10 cigarettes per day 3. current DSM-IV diagnosis of schizophrenia or schizoaffective disorder and stable medication regimen 4. medically healthy as determined by screening criteria 5. urine cotinine level ≥ 100 ng/ml (NicAlert® reading ≥ 3) 6. agrees to wear a head mounted display (HMD) for up to 45 minutes 7. participant able to complete the Evaluation to Sign Consent (ESC) with a minimum score of 80% on ESC. Exclusion criteria 1. interest in reducing or quitting tobacco use within the past 3 months 2. treatment for tobacco dependence in the past 3 months 3. use of nicotine replacement products, bupropion, or varenicline in the past 3 months 4. DSM-IV diagnosis of active alcohol or substance abuse in the past 1 month or dependence within the past 6 months 5. current use of any medication that would interfere with the protocol in the opinion of PI or investigators 6. history of head injury, seizures, or stroke 7. pregnant, nursing, or planning to become pregnant during the study 8. positive urine toxicology screen for substances other than those used for therapeutic purposes: Participants who have an initial positive urine toxicology screen for substances other than those used for therapeutic purposes will will have the opportunity to return within two weeks for a second toxicology screen. If at that time the results are again positive, the participant will be excluded |
Resultat
Mesures de resultats primaris
1. Relationship between pre-identified environmental cues/triggers (social, environmental, or emotional cues) and their effects on the elicitation of craving in smokers with schizophrenia [1 Week]