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Expert Opinion on Investigational Drugs 2013-Feb

Analysis of Pogostemon cablin from pharmaceutical research to market performances.

Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
L'enllaç es desa al porta-retalls
Meiwan Chen
Jinming Zhang
Yunfeng Lai
Shengpeng Wang
Peng Li
Jian Xiao
Chaomei Fu
Hao Hu
Yitao Wang

Paraules clau

Resum

BACKGROUND

Pogostemon cablin (P. cablin), called Ciruicao or Guanghuoxiang, is a well-known Chinese materia medica in southeast Asia that is widely used in gastrointestinal disease and exterior syndromes, being confirmed by both in vitro and in vivo studies. To exploit this traditional medicine that adequately fits modern drugs, however, a comprehensive review about its pharmacy research and market performance is extremely necessary.

METHODS

This article reviews various components extracted from this plant as well as the biological activities derived from those chemical compositions. The authors summarize the quality evaluation and highlight the therapeutic effects of P. cablin, such as antiviral activities, antioxidation effect, antiinflammatory, analgesic activities, and intestinal barrier function protection. The preparation profile of P. cablin and some future related research were also described in this review. Last but not least, a market performance analysis was conducted.

CONCLUSIONS

P. cablin has beneficial therapeutic potential as an effective adaptogenic herbal remedy in clinic. Molecular mechanisms and active targets of P. cablin compounds, the qualitative and quantitative standard of P. cablin, as well as novel drug delivery systems of P. cablin, would be developed.

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