Farmakologiia i toksikologiia
[Effect of anaprilin on the tyrosine hydroxylase activity of the oral mucosa in dogs with experimental stomatitis].
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Resum
It was shown that in dogs with experimental aphthous stomatitis (ligation of the common bile duct) tyrosine hydroxylase activity and content of catecholamines (CA) in the oral mucosa were increased. Blockade of beta-adrenoreceptors caused by anaprilin (1 mg/kg) led to the further increase of tyrosine hydroxylase activity. A relative decrease of CA content was simultaneously observed.
