Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1985
Selenium prevents mercuric chloride induced acute osmoregulatory failure without glutathione peroxidase involvement in the black bullhead (Ictalurus melas).
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Resum
The relationship between coelomic injections of mercuric chloride doses and osmoregulatory responses was measured. Response parameters were weight increases and blood osmolarity decreases 72 hr after dose administration. Massive edema and large decreases in blood osmolarity could be completely prevented by subcutaneous injections of equimolar sodium selenite. Mercury induced damage did not involve alterations of either selenium-dependent or non-selenium-dependent glutathione peroxidase activities.