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11 resultats
Analgesic and anti-inflammatory effects of aqueous extract of Zea mays husk in male Wistar rats.
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The analgesic and anti-inflammatory activities of Zea mays husk extract (25, 50, 100, and 200 mg/kg of body weight) were investigated in rats. The hot plate and formalin-induced paw licking models were used to assess analgesic effects of the extract, whereas the carrageenan and cotton pellet models
Use of force plate analysis to assess the analgesic effects of etodolac in horses with navicular syndrome.
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OBJECTIVE
To evaluate the musculoskeletal analgesic effect of etodolac administered PO every 12 or 24 hours in chronically lame horses by use of force plate analysis.
METHODS
22 horses with navicular syndrome.
METHODS
Horses received etodolac (23 mg/kg, PO, q 12 h; n = 7), etodolac (23 mg/kg, PO, q
Honokiol for the Treatment of Neonatal Pain and Prevention of Consequent Neurobehavioral Disorders.
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This study examined the short- and long-term neuroprotective and analgesic activity of honokiol (a naturally occurring lignan isolated from Magnolia) on developing brains in neonates exposed to inflammatory pain, known to cause neuronal cell death. Postnatal day 4 (P4) neonatal rat pups were
Dietary omega-3 fatty acids may be associated with increased neuropathic pain in nerve-injured rats.
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Certain dietary proteins and oils are capable of decreasing chronic neuropathic pain levels in rats after partial sciatic nerve ligation injury. We tested, for the first time, the role of dietary polyunsaturated fatty acids in suppressing pain in partial sciatic nerve ligation-injured rats. Six
NTP toxicity studies of carisoprodol (CAS No. 78-44-4) administered by Gavage to F344/N rats and B6C3F1 mice.
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[carisoprodol structure: see text] Carisoprodol is a widely used skeletal muscle relaxant and analgesic and is available as a prescription drug. Comparative studies were conducted to determine the toxicity of carisoprodol administered in corn oil and in 0.5% methylcellulose by gavage. Carisoprodol
Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome.
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OBJECTIVE
To evaluate the efficacy of the essential omega-6 fatty acid Gammalinolenic acid (GLA) on fatigue associated with primary Sjögren's syndrome.
METHODS
Ninety patients with primary Sjögren's syndrome (with or without signs of autoimmunity) entered a 6-month double blind placebo-controlled
Chronic intragastric infusion of ethanol-containing diets induces CYP3A9 while decreasing CYP3A2 in male rats.
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The CYP3A subfamily is the most abundant of the human hepatic cytochrome P450 enzymes. They mediate the biotransformation of many drugs, including a number of psychotropic, cardiac, analgesic, hormonal, immunosuppressant, antineoplastic, and antihistaminic agents. We studied diet/ethanol
Absence of genotoxic activity of beta-myrcene in the in vivo cytogenetic bone marrow assay.
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beta-Myrcene (MYR, 7-methyl-3-methylene-1,6 octadiene) is a peripheral analgesic substance and one of the major constituents of lemongrass oil (Cymbopogon citratus, Stapf), a plant widely used in Brazilian folk medicine. In the present study the genotoxicity of MYR was evaluated in vivo using the
Study on embryo-foetotoxicity of beta-myrcene in the rat.
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beta-Myrcene is a constituent of many essential oils that have been used extensively in cosmetic fragrances and as flavouring additives in the food industry. Recently, this monoterpene was reported to be an analgesic substance. Notwithstanding the widespread use of myrcene and essential oils
Peri- and postnatal developmental toxicity of beta-myrcene in the rat.
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beta-Myrcene (MYR) and essential oils containing this monoterpene have been widely used as scenting agents in cosmetics, detergents, soaps, and as flavouring additives in food and beverages. Recently, MYR was reported to be an analgesic substance and the active principle of lemongrass tea. Despite
Neurobehavioral study of the effect of beta-myrcene on rodents.
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Tea prepared from lemongrass (Cymbopogon citratus) is used for its supposed anxiolytic, hypnotic and analgesic properties in Brazilian folk medicine. beta-Myrcene, a major constituent of lemongrass, produces analgesia in rodents but there is some controversy about whether this action is central or
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