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8 resultats
Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity
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FIELD OF THE INVENTION
This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
BACKGROUND OF THE INVENTION
Obesity, which is an excess of body fat relative to lean body mass, is a chronic disease
Biphenyl-pyrazolecarboxamide compounds
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TECHNICAL FIELD OF THE INVENTION
The present invention relates to biphenyl-pyrazolecarboxamide compounds. The invention further provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by
Biphenyl derivatives useful as glucagon receptor antagonists
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FIELD OF THE INVENTION
The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic
Halo-biphenyl tertiary alcohols useful in therapy in the treatment of atherosclerosis
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The present invention relates to new derivatives of halo-biphenyl tertiary alcohols having lipid-reducing, cholesterol-reducing and anorectic properties, a method of preparing them, and their use as medicaments useful in the treatment and prevention and atherosclerotic disturbances and obesity.
In
Biphenyl amide lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
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This invention relates to compounds that are inhibitors of 11-.beta.-hydroxysteroid dehydrogenase type 1 ("11-.beta.-HSD1"), and to pharmaceutical compositions thereof, and the uses of these compounds and compositions in the treatment of the human or animal body, and to novel intermediates useful in
7-[(4'-trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and methods of inhibiting the secretion of apolipoprotein B
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FIELD OF THE INVENTION
This invention relates to compounds that inhibit the secretion of apolipoprotein B, and to methods of treating and/or preventing atherosclerosis, obesity, diabetes, hyperlipidemia, hyperlipoproteinemia, hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia,
7[4'-trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and method of inhibiting the secretion of apolipoprotein B
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FIELD OF THE INVENTION
This invention relates to compounds that inhibit the secretion of apolipoprotein B, and to methods of treating and/or preventing atherosclerosis, obesity, diabetes, hyperlipidemia, hyperlipoproteinemia, hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia,
Pharmaceutical composition for preventing and teating endocrine disrupting chemicals-induced diseases and treating method using the same
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims the priority of Korean Patent Application No. 10-2016-0115867 filed on Sep. 8, 2016, in the Korean Intellectual Property Office, the disclosure of which is incorporated herein by reference.
BACKGROUND
1. Technical Field
The present
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