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broad/antifúngic

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Broad-spectrum antiviral therapeutics.

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Currently there are relatively few antiviral therapeutics, and most which do exist are highly pathogen-specific or have other disadvantages. We have developed a new broad-spectrum antiviral approach, dubbed Double-stranded RNA (dsRNA) Activated Caspase Oligomerizer (DRACO) that selectively induces

Azithromycin: The First Broad-spectrum Therapeutic

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The Strategic Plan for Biodefense Research by the U.S. Department of Health and Human Services demarcates the need for drugs which target multiple types of pathogens to prepare for infectious threats. Azithromycin is one such broad-spectrum therapeutic that is both included in the University of

Azithromycin: The First Broad-spectrum Therapeutic

Només els usuaris registrats poden traduir articles
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The Strategic Plan for Biodefense Research by the U.S. Department of Health and Human Services demarcates the need for drugs which target multiple types of pathogens to prepare for infectious threats. Azithromycin is one such broad-spectrum therapeutic that is both included in the University of

Broad spectrum antifungal agents in otomycosis.

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The in vitro inhibitory activities of four currently used antimycotic agents (clotrimazole, econazole, miconazole and cyclopirox-olamine) against 304 fungal isolates comprising 51 species from 14 genera of moulds and yeasts, using a serial dilution procedure, were studied. Clotrimazole and econazole

Terconazole - a new broad-spectrum antifungal.

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Terconazole, a new triazole ketal, is found to be highly active in vitro on a wide range of yeasts and mycelium-forming fungi. The in vitro activity depends largely on the medium used. In vitro it is a potent antifungal agent in preventing the morphogenetic transformation of the yeast into the

Posaconazole: a broad-spectrum triazole antifungal.

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Posaconazale is a new triazole drug being investigated in phase III clinical trials for the treatment and prevention of invasive fungal infections. In-vitro and in-vivo studies showed that posaconazole has broad-spectrum activity against most Candida species, Cryptococcus neoformans, Aspergillus

[Econazol, a new broad-spectrum antimycotic].

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[Ketoconazole a new broad spectrum antimycotic].

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Broad therapeutic uses of atypical antipsychotic medications.

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The atypical antipsychotics have a low incidence of extrapyramidal side effects (EPS), have improved tardive dyskinesia profiles, and have a broad range of therapeutic efficacy. These agents offer important therapeutic advantages that extend beyond their initial regulatory approval in several

Posaconazole: a new broad-spectrum antifungal agent.

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The rising incidence of invasive fungal infections and the emergence of broader fungal resistance have led to the need for novel antifungal agents. Posaconazole is a new member of the triazole class of antifungals. It is available as an oral suspension and has a favorable toxicity profile, has

[Clotrimazol, a new broad-spectrum antimycotic agent].

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Anticandidal activities of terconazole, a broad-spectrum antimycotic.

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Terconazole is a new triazole ketal derivative with broad-spectrum in vitro and in vivo antifungal activities. This study further characterizes the effects of terconazole in vitro on yeast cell growth, viability, and morphology. Terconazole inhibited the growth of Candida albicans ATCC 44859 in a

Mycotic vulvovaginitis: a broad overview.

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The incidence of mycotic vulvovaginitis is rising dramatically in the United States mainly because of an increase in infections caused by Candida species. Accurate diagnosis depends on culture techniques that will yield correct identification of fungal pathogen(s). Recurrences are common and require

The chemokine system: novel broad-spectrum therapeutic targets.

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Chemokines are cytokines that specifically direct the trafficking of immune cells in the body. They offer a novel point of therapeutic intervention, as inhibiting specific chemokines and receptors could prevent the excessive recruitment of leukocytes to sites of inflammation. This approach could be

An endophytic Coniochaeta velutina producing broad spectrum antimycotics.

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An endophyte (PC27-5) was isolated from stem tissue of Western hemlock (Tsuga heterophylla) in a Pacific Northwest temperate rainforest. Phylogenetic analyses, based on ITS-5.8S rDNA and 18S rDNA sequence data, combined with cultural and morphological analysis showed that endophyte PC27-5 exhibited
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