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5 resultats
Evaluation of some genes and proteins involved in Apoptosis on human chronic myeloid leukemia cells (K562 cells) by Datura innoxia Leaves Aqueous Extract.
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Datura innoxia (D.innoxia) has an extensive usage in traditional medicine and can also be used for intervention therapy in order to treat cancer. Despite of accomplishing some researches on D.innoxia mechanism, still our knowledge is very little about exact D.innoxia apoptotic
In vitro cytotoxicity of polyphenols from Datura innoxia aqueous leaf-extract on human leukemia K562 cells: DNA and nuclear proteins as targets.
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Leukemia is a malignant hematological disease and chemotherapy remains the most important tool for its treatment. As chemotherapy has many side effects and could lead to resistance in cancer cells, plant-based medication is being considered as a new strategy in cancer treatment. Datura
Preclinical anticancer studies on the ethyl acetate leaf extracts of Datura stramonium and Datura inoxia
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Background: Cancer is a horrific disease relentlessly affecting human population round the globe. Genus Datura encompasses numerous species with reported medicinal uses. However, its potential as a source of natural anticancer agents is
Cytotoxic withanolides from the flowers of Datura metel.
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Chemical investigation of a methanol extract of the flowers of Datura metel has led to the isolation of 10 new withanolides, withametelins I-P (1-8), 1,10-seco-withametelin B (9), and 12beta-hydroxy-1,10-seco-withametelin B (10), together with seven known withanolides. The structures of 1-10 were
Extraction optimization of medicinally important metabolites from Datura innoxia Mill.: an in vitro biological and phytochemical investigation.
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BACKGROUND
The present study aims to probe the impact of polarity dependent extraction efficiency variation on pharmacological spectrum of Datura innoxia Mill. in order to reconnoiter its underexplored therapeutic potential.
METHODS
A range of solvent extracts was subjected to phytochemical and
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