Fluids will be stopped at 8am on POD 1 and patients will be started on a moderate fluid restriction on POD #3 based on their weight (1000 cc/24 hours for patients who weigh <=100 kg and 1200 cc/24 hours for patients who weigh > 100kg)

Hyponatremia

Hyponatremic

Pituitary Tumor

Pituitary

Surgery

Patients will be started on a weight-based intravenous fluid replacement with D5 ½ NS on POD 0 (75 cc/hr for patients < 70kg, 100 cc/hr for patients 70-100kg, and 125 cc/hr for patients >100kg). Patients will be allowed to drink water freely after surgery on POD #0. Fluids will be stopped at 8am on POD 1 and patients will be started on a moderate fluid restriction on POD #3 based on their weight (1000 cc/24 hours for patients who weigh <=100 kg and 1200 cc/24 hours for patients who weigh > 100kg). Prior to initiation of a fluid restriction all of the following criteria have to be met:
Serum Na level must be < 145 mEq/l
Patient should be taking fluids by mouth
Patient should not have evidence of DI (as determined by endocrine team following patient) If a patient in Fluid Restricted group develops DI, the fluid restriction will be stopped/not initiated.

Fluid Restricted Group

Barnes Jewish Hospital

Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)

Early Fluid Restriction to Prevent Delayed Hyponatremia Following Pituitary Surgery

Washington University School of Medicine

Skull Base Neoplasms

Assiut University

Skull Base Reconstruction After Endonasal Cranio-endoscopic Resection Using Autologus Grafts

bone window axial, coronal and sagittal cuts to measure preoperative skull base defect size

Coronal, axial and sagittal MRI in T1 and T2 signals measures postoperative tumor, to assess the repaired defect after the surgery

Coronal, axial and sagittal MRI in T1 and T2 signals to assess the repaired defect after the surgery

Coronal, axial and sagittal MRI in T1 and T2 signals to assess the repaired defect after the surgery, recurrence of tumor

identification of possible complication that will occur during resection of skull base and removal of tumors

history of CSF leakage confirmed by endoscopic examination

second surgical intervention to explore the grafted defect

using 4 mm 0-degree endoscope to measure graft condition and visualize any CSF fistula

Coronal, axial and sagittal MRI in T1 and T2 signals measures preoperative tumor size

identification of the type of the pathology

Ahmed Gamal Sholkamy

D5Normal Saline

Normal Saline

Total

Sex: Female, Male

Region of Enrollment

Measurement of serum ketones by bedside ketone meter before and after administration of IVF for both groups to determine a change in serum ketones. The hypothesis is that dextrose containing IVF will lead to a decrease in serum ketones in children with acute gastroenteritis who require IV rehydration.

Measurement of Serum Ketones Before and After Administration of Intravenous Fluids for Acute Gastroenteritis

10cc/kg 5% Dextrose (D5) in Normal Saline (NS) (D5NS), followed by 30cc/kg Normal Saline (NS)

diabetes insipidus/cefalàlgia

Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)

Skull Base Reconstruction After Endonasal Cranio-endoscopic Resection Using Autologus Grafts

IV Glucose for Dehydration Treatment

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