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Pàgina 1 des de 1685 resultats
The involvement of proline-rich 15 in early conceptus development in sheep.
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The ruminant conceptus undergoes a period of elongation that is required for maternal recognition of pregnancy, prior to attaching to the endometrium. The purpose of these studies was to investigate the role of proline-rich 15 (PRR15) in the sheep conceptus by examining mRNA expression, protein
The Proline/Citrulline Ratio as a Biomarker for OAT Deficiency in Early Infancy.
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Deficiency of ornithine-δ-aminotransferase (OAT) in humans results in gyrate atrophy. Early diagnosis may allow initiation of treatment before irreversible damage has occurred. However, diagnosis is commonly delayed well into adulthood because of the nonspecific character of initial symptoms. Here,
Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.
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cis-trans isomerization of proteins phosphorylated by proline-directed kinases is proposed to control numerous signaling molecules and is implicated in the pathogenesis of Alzheimer's and other diseases. However, there is no direct evidence for the existence of cis-trans protein isomers in vivo or
Proline metabolism in pollen: degradation of proline during germination and early tube growth.
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Proline degradation inPetunia pollen germinated in vitro was studied in cultures supplemented with [(14)C]proline labeled at different positions. Despite its abundance in the cell, this amino acid is only a minor substrate for respiration. Proline is partially converted via the citrate cycle into
[The significance of serum proline iminopeptidase in the early diagnosis of renal osteodystrophy].
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The Clostridium difficile proline racemase is not essential for early logarithmic growth and infection.
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Proline racemase (PrdF), which is important for energy metabolism via the Stickland pathway and is unique to certain clostridia, was investigated as a potential anti-Clostridium difficile target by examining its effects on the growth and virulence of C. difficile. Inactivation of PrdF by insertional
Proline supplementation mitigates the early stage of liver injury in bile duct ligated rats.
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Two tobacco proline dehydrogenases are differentially regulated and play a role in early plant development.
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Proline dehydrogenase is the rate-limiting enzyme in proline degradation and serves important functions in the stress responses and development of plants. We isolated two tobacco proline dehydrogenases, NtPDH1 and NtPDH2, in the course of screening for genes upregulated in stressed tobacco
Efficacy of L-proline administration on the early responses during cutaneous wound healing in rats.
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Proline (Pro) plays a versatile role in cell metabolism and physiology. Pro and hydroxypro are major imino acids present in collagen, an important connective tissue protein, essential for wound healing, which is a primary response to tissue injury. This study explains the role of L-pro on cutaneous
A new proline-rich early nodulin from Medicago truncatula is highly expressed in nodule meristematic cells.
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We cloned and characterized MtPRP4, a new member of the repetitive proline-rich protein gene family in Medicago truncatula. The sequence of MtPRP4 predicts a 62-kD protein consisting of a 22-amino acid N-terminal signal peptide and a 527-amino acid repetitive proline-rich domain composed of three
Proline-rich sequence recognition: I. Marking GYF and WW domain assembly sites in early spliceosomal complexes.
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Proline-rich sequences (PRS) and their recognition domains have emerged as transposable protein interaction modules during eukaryotic evolution. They are especially abundant in proteins associated with pre-mRNA splicing and likely assist in the formation of the spliceosome by binding to GYF and WW
Characterization of the soybean early nodulin cDNA clone GmENOD55.
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Two cDNA clones of the soybean early nodulin GmENOD55 were characterized. These clones may represent two members of the soybean early nodulin gene family GmENOD55. GmENOD55 has an N-terminal signal peptide and it contains an internal domain consisting of proline and serine residues. Analyses of
Potential plasma lipid biomarkers in early-stage breast cancer.
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OBJECTIVE
To find new biomarkers for early diagnosis of breast cancer.
RESULTS
847 lipid species were identified from 78 plasma samples (37 breast cancer samples and 41 healthy controls) by ultra HPLC coupled with quadrupole time-of-flight tandem mass spectrometry. These include 321
Early stages of maillard reaction in dehydrated orange juice.
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The formation of furoylmethyl derivatives of amino acids as indicators of the early stages of Maillard reaction in dehydrated orange juices and model systems was studied. In stored dehydrated orange juices, the presence of furoylmethyl derivatives of arginine, asparagine, proline, alanine, glutamic
Effect of enhanced macrophage function on early wound healing.
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Although the macrophage is important to wound healing, research has focused on its relationship to fibroblast and collagen synthesis. This study was designed to assess effects of enhanced macrophage function on early wound healing, before established collagen synthesis. Sprague-Dawley rats had
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