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endolymphatic hydrops/arginina
L'enllaç es desa al porta-retalls
12 resultats
Effect of electroacupuncture on arginine vasopressin-induced endolymphatic hydrops.
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Arginine vasopressin-aquaporin-2 pathway-mediated dehydration effects of electroacupuncture in guinea pig model of AVP-induced endolymphatic hydrops.
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OBJECTIVE
To investigate the effects of electroacupuncture (EA) on endolymphatic hydrops (EH) and the regulation of arginine vasopressin (AVP)-aquaporin-2 (AQP2) pathway in guinea pigs.
METHODS
EH was induced in male guinea pigs by an intraperitoneal injection of AVP. For the treatment, EA was
[Arginine vasopressin-aquaporin2 signal pathway and endolymphatic hydrops].
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Effects of arginine vasopressin on auditory brainstem response and cochlear morphology in rats.
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OBJECTIVE
This study was conducted to evaluate the relationship between hearing and cochlear histopathology after arginine vasopressin administration in rats.
METHODS
A total of 30 Wistar rats were injected with either 0.02 unit/g of arginine vasopressin or the same amount of isotonic saline
Summating potential in the guinea pig cochlea after perilymphatic perfusion with arginine-vasopressin.
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We hypothesized that arginine-vasopressin (AVP), the natural vasopressin in the guinea pig, might increase the cochlear summating potential, indicating an increase in endolymphatic volume. Guinea pig cochleas were perfused with artificial perilymph for 15 min, with or without AVP (2 x 10(-6) M). In
[Effect of vasopressin on aquaporin 7 expression in rat inner ear].
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OBJECTIVE
To study the effect of vasopressin on aquaporin 7 (AQP7) expression in rat inner ear and reveal the possible role of aquaporins in the formation of endolymphatic hydrops induced by vasopressin.
METHODS
Wistar rats were intraperitoneally injected with 50 microg/kg arginine vasopressin once
Vasopressin and oxytocin receptor mRNAs are expressed in the rat inner ear.
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The cause of endolymphatic hydrops, a characteristic finding in Menière's disease, is not known. To study the possible involvement of the neurohormones vasopressin and oxytocin in this condition, we investigated whether transcripts of the genes encoding the arginine vasopressin (AVP) and oxytocin
Effects of vasopressin on gene expression in rat inner ear.
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Vasopressin regulates water excretion from the kidney by increasing water permeability of the collecting duct as a hormone secreted from the posterior pituitary. A clinical study reported that plasma levels of arginine vasopressin were significantly higher in patients suffering from Meniere's
Claudin expression in the rat endolymphatic duct and sac - first insights into regulation of the paracellular barrier by vasopressin.
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Hearing and balance functions of the inner ear rely on the homeostasis of the endolymphatic fluid. When disturbed, pathologic endolymphatic hydrops evolves as observed in Menière's disease. The molecular basis of inner ear fluid regulation across the endolymphatic epithelium is largely unknown. In
Ménière's Disease Pathophysiology: Endolymphatic Sac Immunohistochemical Study of Aquaporin-2, V2R Vasopressin Receptor, NKCC2, and TRPV4.
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Objectives Endolymphatic sac (ELS) pathophysiology in Ménière's disease (MD) remains poorly understood. We identified from the literature a group of proteins expressed on the ELS and involved in endolymph volume regulation: aquaporin-2 (AQP2), vasopressin receptor V2R, sodium potassium chloride
Autoregulation of cochlear blood flow in the hydropic guinea pig.
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Previous data suggest that regulation of cochlear blood flow (CBF) may be abnormal in the hydropic guinea pig. The purpose of this study was to employ the technique of anterior inferior cerebellar artery (AICA) occlusion to measure CBF autoregulation in experimental endolymphatic hydrops. This study
Aquaporins as potential drug targets for Meniere's disease and its related diseases.
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The homeostasis of water in the inner ear is essential for maintaining function of hearing and equilibrium. Since the discovery of aquaporin water channels, it has become clear that these channels play a crucial role in inner ear fluid homeostasis. Indeed, proteins or mRNAs of AQP1, AQP2, AQP3,
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