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8 resultats
Development of a comprehensive quality control method for the quantitative analysis of volatiles and lignans in Magnolia biondii Pamp. by near infrared spectroscopy.
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The quality of drug is vital to its curative effect, thus it is important to develop a comprehensive quality control method for commonly used drugs. In this study, we developed a Gas chromatography-mass spectrometry separation method for the qualitative and quantitative analysis of volatiles,
Isolation and purification of lignans from Magnolia biondii Pamp by isocratic reversed-phase two-dimensional liquid chromatography following microwave-assisted extraction.
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The dried flower buds of Magnolia biondii Pamp are one of the most widely used medicinal plants officially listed in the Chinese Pharmacopoeia. A 2-D column-switching system without sample loop trapping, where two columns were switched directly via a six-port two-position switching valve, was
Two new constituents from the leaves of magnolia coco
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A new amide, magnolamide (1), and a new lignan, magnolone (2), whose structures were determined on the basis of spectral analysis, were found in the leaves of Magnolia coco. Eleven known compounds (episesamin, sesamin, magnolol, fargesin, aschantin, epieudesmin, syringaresinol,
[Biologically active lignins from Magnolia biondii Pamp].
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Guided by PAF induced platelet aggregation, six active lignins were isolated from the flower buds of Magnolia biondii and identified as fargesin, demethoxyaschantin, aschantin, pinoresinol dimethyl ether, magnolin, lirioresinol-B dimethyl ether. The 13CNMR and CD data were reported and the
Cell membrane chromatography coupled online with LC-MS method to screen anti-anaphylactoid components from Magnolia biondii Pamp. targeting on Mas-related G protein-coupled receptor X2.
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Mas-related G protein-coupled receptor X2 was a mast cell specific receptor mediating anaphylactoid reactions by activating mast cells degranulation, it was also identified as a target for modulating mast cell-mediated anaphylactoid and inflammatory diseases. The anti-anaphylactoid drugs used
Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco.
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Based on the inhibition of Cu(2+)-induced LDL oxidation as marker, the major antioxidants in the fruits of Forsythia suspensa and the stems of Magnolia coco were identified. Of these bioactive tetrahydrofurofuran lignans, pinoresinol, phillygenin, and syringaresinol were more potent than probucol.
5-lipoxygenase-inhibitory constituents from Schizandra fructus and Magnolia flos.
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In order to establish the antiallergic properties of Schisandra fructus and Magnolia flos, several compounds isolated from these plants were tested for 5-lipoxygenase (5-LOX) inhibitory activity in vitro, for the first time. The compounds including schizandrins, schisandrols, gomisins, fargesin,
Suppression of inducible nitric oxide synthase expression by furfuran lignans from flower buds of Magnolia fargesii in BV-2 microglial cells.
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Activated microglia produces diverse neurotoxic factors such as nitric oxide (NO) and tumor necrosis factor-alpha that serve as apoptotic inducers resulting in various neurodegenerative diseases. The inhibition of microglia-derived NO production by inducible nitric oxide synthase (iNOS) has been
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