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Pàgina 1 des de 57 resultats
Elevated albumin in retinas of monkeys with experimental glaucoma.
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OBJECTIVE
To establish the identity of a prominent protein, approximately 70 kDa, that is markedly increased in the retina of monkeys with experimental glaucoma compared with the fellow control retina, the relationship to glaucoma severity, and its localization in the retina.
METHODS
Retinal
Vitreous albumin redox state in open-angle glaucoma patients and controls: a pilot study.
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Reduced plasma cortisol binding to albumin in ocular hypertension and primary open-angle glaucoma.
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OBJECTIVE
To compare plasma cortisol binding as well as total plasma cortisol, free cortisol and percent free cortisol in normals, ocular hypertensives and primary high pressure open-angle glaucomas.
METHODS
Blood samples were obtained on outpatient visits of 18 normals, 19 ocular hypertensives and
Lysozyme, alfa-1-antitrypsin and serum albumin in tear fluid of timolol treated glaucoma patients with and without symptoms of dry eyes.
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Determination of tear lysozyme, alfa-1-antitrypsin and serum albumin was performed in the tear fluid of 24 glaucoma patients on maintenance treatment with timolol. In 7 patients with symptoms of dry eye decreased levels of tear lysozyme and increased levels of alfa-1-antitrypsin and serum albumin
Thiol-Disulfide Homeostasis and Serum Ischemia Modified Albumin Levels in Patients with Primary Open-Angle Glaucoma.
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Aim: Glaucoma is an optic neuropathy causing progressive impairment of visual functions. We aimed to assess the alterations in thiol-disulfide homeostasis and serum ischemia modified albumin (IMA) levels, which are the determinants of antioxidant status, in patients with primary open-angle
Animal model for uveitic glaucoma.
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BACKGROUND
This study was carried out in order to improve the understanding of the pathogenesis of uveitic glaucoma.
METHODS
Uveitis was induced in 48 Lewis rats by S-antigen injection. Intraocular pressure (IOP) was measured by Tono-Pen-2 daily for 24 days in 16 animals. Histopathology was
Investigation of the 'fines' hypothesis of primary open-angle glaucoma: the possible role of alpha-crystallin.
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Primary open-angle glaucoma is a disease caused by an increase in intraocular pressure due to a decreased facility of outflow of aqueous humor through the trabecular meshwork. The etiology of primary open-angle glaucoma is currently unknown, but it has been suggested that one possible mechanism may
The evaluation of the oxidative stress parameters in patients with primary angle-closure glaucoma.
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OBJECTIVE
To clarify the presence of oxidative stress in patients with primary angle-closure glaucoma (PACG) and to investigate the relationship between oxidative stress and PACG.
METHODS
Fifty patients with primary angle-closure glaucoma and fifty healthy controls of matched age and gender were
[Is increased outflow resistance in glaucoma simplex caused by regional differences in trabecular meshwork density? Some methodologic and morphologic considerations clarifying this question].
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In 1953, Goldmann observed that outflow resistance increases in an underperfused meshwork and concluded that only continuous perfusion keeps the outflow channels open. In primary open-angle glaucoma densifications occur beneath the inner wall of Schlemm's canal. They consist of fine fibrillary
A technique for shotgun proteomic analysis of the precorneal tear film in dogs with naturally occurring primary glaucoma.
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IgG, albumin and total IgG index in the aqueous humour of eyes with pseudoexfoliation syndrome.
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IgG and albumin in the aqueous humour and serum were studied using kinetic nephelometry, carried out on 34 eyes with pseudoexfoliation and 31 normal eyes (control group). The results show a rupture in the hemato-aqueous barrier for IgG and albumin in the group of eyes with pseudoexfoliation and
Microvascular effects of selective prostaglandin analogues in the eye with special reference to latanoprost and glaucoma treatment.
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Prostaglandin F(2alpha) analogues have recently been introduced on the market for glaucoma treatment. While these drugs have a well-documented intraocular pressure reducing effect only a limited number of studies have been published regarding their effects on the microvasculature in the eye. Since
Albuminuria and Primary Open-Angle Glaucoma: the Singapore Chinese Eye Study (SCES)
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Aims: To determine the association between albuminuria and primary open-angle glaucoma (POAG).
Methods: Participants of the Singapore Chinese Eye study were recruited and
Is primary open angle glaucoma caused by small proteins?
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Primary open angle glaucoma is a disease which is characterized by a decreased facility of outflow of aqueous humor from the anterior segment of the eye. Analyses by gel exclusion chromatography of the aqueous humor of normal monkeys have shown that the proteins in this fluid range in size from
Doxium (calcium dobesilate) reduces blood hyperviscosity and lowers elevated intraocular pressure in patients with diabetic retinopathy and glaucoma.
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In a double-blind randomized clinical trial, 79 non-insulin-dependent diabetic subjects with early retinopathy and open-angle glaucoma received orally either three 500-mg capsules of Doxium (calcium dobesilate) daily for 6 months (41 patients) or three placebo capsules daily for the same period (38
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