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Tacrolimus for induction therapy of diffuse proliferative lupus nephritis: an open-labeled pilot study.

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BACKGROUND Tacrolimus is a relatively new calcineurin inhibitor that has been increasingly used in transplant medicine. The objective of the current work is to report our preliminary experience with tacrolimus in the treatment of diffuse proliferative glomerulonephritis in systemic lupus

[Long-term effects of cyclosporine A in children with steroid-resistant idiopathic nephrotic syndrome and outcomes of the patients].

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OBJECTIVE To observe the effects of long-term cyclosporine A (CsA) treatment in 20 children with steroid-resistant idiopathic nephrotic syndrome (SRNS) and analyse the relevant influencing factors of CsA therapy. METHODS Twenty children with SRNS received CsA therapy for 2 years between February
BACKGROUND To examine whether tacrolimus is more effective and safe than cyclosporine (CsA) in inducing remission in patients with steroid-resistant nephrotic syndrome (SRNS). METHODS Randomized controlled trial, nonblind, parallel group. METHODS Tertiary-care hospital; 41 consecutive patients with

Cyclosporin A treatment in inflammatory bowel disease.

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The effect of cyclosporin A in acute and chronically active inflammatory bowel disease was tested in 11 patients with Crohn's disease and two with ulcerative colitis who had exhibited a poor response to at least eight weeks of conventional therapy. Trough levels of the drug in the therapeutic range
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