Catalan
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
hypertrichosis/potassium
L'enllaç es desa al porta-retalls
Pàgina 1 des de 25 resultats
Skin and hair abnormalities of Cantu syndrome: A congenital hypertrichosis due to a genetic alteration mimicking the pharmacological effect of minoxidil.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Cantu syndrome is an autosomal dominant disorder, first described by Cantu in 1982, that is characterized by congenital hypertrichosis, characteristic facial anomalies and cardiomegaly. Recent investigations have revealed that this syndrome is caused by mutations of ABCC9, which encodes a regulatory
Topical sulfonylurea as a novel therapy for hypertrichosis secondary to diazoxide, and potentially for other conditions with excess hair growth.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
It is hypothesized that a topical application of a sulfonylurea drug, which can inhibit the ATP-sensitive potassium-gated channels (Kir6.X/SUR) present in human hair bulb tissues, will inhibit hair growth in a targeted manner. Diazoxide is used to treat severe hypoglycemia due to hyperinsulinism of
A novel mutation in the KCNJ8 gene encoding the Kir6.1 subunit of an ATP-sensitive potassium channel in a Japanese patient with Cantú syndrome.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Cantú syndrome (CS: OMIM239850) is an autosomal dominant inherited disorder characterized by congenital hypertrichosis, coarse facial features, osteochondrodysplasia and cardiomegaly. CS is caused by gain-of-function (GOF) mutations in the ABCC9 (ATP binding cassette subfamily member 9) and KCNJ8
A new type of ATP-sensitive potassium channelopathy : Cantú syndrome.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Multiple mutations in Kir6.x and SURx genes have implicated ATP-sensitive potassium (KATP) channels and, as a result, have led to diverse diseases, ranging from diabetes and hyperinsulinism to cardiac arrhythmias and cardiovascular disease. These diseases are referred to as KATP channelopathies.
Potassium channel conductance: a mechanism affecting hair growth both in vitro and in vivo.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
The opening of intracellular potassium channels has been suggested as a mechanism regulating hair growth. Enhancing the flux of potassium ions is a mechanism shared by several structurally diverse antihypertensive agents including minoxidil sulfate (the active metabolite of minoxidil), pinacidil,
Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Cantu syndrome (CS) is a condition characterized by a range of anatomical defects, including cardiomegaly, hyperflexibility of the joints, hypertrichosis, and craniofacial dysmorphology. CS is associated with multiple missense mutations in the genes encoding the regulatory sulfonylurea receptor 2
Diazoxide for the Treatment of Hypoglycemia Resulting From Dumping Syndrome in a Child.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Dumping syndrome-associated hypoglycemia is caused by an exaggerated hyperinsulinemic response to glucose absorption in the small intestine. Diazoxide acts on the ATP-sensitive potassium channels and prevents insulin secretion and, thus, should be beneficial for the treatment of hypoglycemia
KATP channels and cardiovascular disease: suddenly a syndrome.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
ATP-sensitive potassium (KATP) channels were first discovered in the heart 30 years ago. Reconstitution of KATP channel activity by coexpression of members of the pore-forming inward rectifier gene family (Kir6.1, KCNJ8, and Kir6.2 KCNJ11) with sulfonylurea receptors (SUR1, ABCC8, and SUR2, ABCC9)
'Splitting versus lumping': Temple-Baraitser and Zimmermann-Laband Syndromes.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
KCNH1 mutations have recently been described in six individuals with Temple-Baraitser syndrome (TMBTS) and six individuals with Zimmermann-Laband syndrome (ZLS). TMBTS is characterized by intellectual disability (ID), epilepsy, dysmorphic facial features, broad thumbs and great toes with
Cantú syndrome: Findings from 74 patients in the International Cantú Syndrome Registry.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Cantú syndrome (CS), first described in 1982, is caused by pathogenic variants in ABCC9 and KCNJ8, which encode the regulatory and pore forming subunits of ATP-sensitive potassium (KATP ) channels, respectively. Multiple case reports of affected individuals have described the various
Cantú syndrome versus Zimmermann-Laband syndrome: Report of nine individuals with ABCC9 variants
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Cantú syndrome (CS) is a rare developmental disorder characterized by a coarse facial appearance, macrocephaly, hypertrichosis, skeletal and cardiovascular anomalies and caused by heterozygous gain-of-function variants in ABCC9 and KCNJ8, encoding heterooctameric ATP-sensitive potassium
Mutation of KCNJ8 in a patient with Cantú syndrome with unique vascular abnormalities - support for the role of K(ATP) channels in this condition.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
KCNJ8 (NM_004982) encodes the pore forming subunit of one of the ATP-sensitive inwardly rectifying potassium (KATP) channels. KCNJ8 sequence variations are traditionally associated with J-wave syndromes, involving ventricular fibrillation and sudden cardiac death. Recently, the KATP gene ABCC9
A Case Report of Scrotal Rejuvenation: Laser Treatment of Angiokeratomas of the Scrotum.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
Scrotal rejuvenation encompasses not only the functional quality but also the aesthetic appearance of the scrotum. It includes medical therapy and procedural interventions to improve scrotal conditions that require morphologic restoration and/or aesthetic alteration. Rejuvenation of the scrotum may
Cyclosporine level at the second hour in pediatric hematopoietic stem cell transplant patients.
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
In this retrospective study, cyclosporine levels at the second hour (C2 levels) were measured during oral cyclosporine intake in 28 pediatric hematopoietic stem cell transplant patients, and the relations between cyclosporine dosage and C0, C2 levels, C2/C0 ratio, and cyclosporine-related adverse
[Controlled clinical study of Consupren versus cyclophosphamide in chronic glomerulonephritis. II. Adverse effects].
Només els usuaris registrats poden traduir articles
Inicieu sessió / registreu-vos
BACKGROUND
The second part of the study was designed to assess Consupren side effects.
RESULTS
The groups of patients studied were described in Part I. Side affects typical of Cy-A were evaluated only in the CS group. Gastrointestinal intolerance, only mild and temporary, was observed in 31%,
La base de dades d’herbes medicinals més completa avalada per la ciència
- Funciona en 55 idiomes
- Cures a base d'herbes recolzades per la ciència
- Reconeixement d’herbes per imatge
- Mapa GPS interactiu: etiqueta les herbes a la ubicació (properament)
- Llegiu publicacions científiques relacionades amb la vostra cerca
- Cerqueu herbes medicinals pels seus efectes
- Organitzeu els vostres interessos i estigueu al dia de les novetats, els assajos clínics i les patents
Escriviu un símptoma o una malaltia i llegiu sobre herbes que us poden ajudar, escriviu una herba i vegeu malalties i símptomes contra els quals s’utilitza.
* Tota la informació es basa en investigacions científiques publicades
