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inositol/inflamació

L'enllaç es desa al porta-retalls
13 resultats

Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents

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BACKGROUND OF THE INVENTION A group of novel phosphatidyl inositol (PI) analogs are found to be effective phospholipase C inhibitors which are useful anti-inflammatory and analgesic agents. Phospholipase C contained in mouse peritoneal macrophages has been linked to the enhanced turnover of

Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents

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BACKGROUND OF THE INVENTION A group of novel sulfonyl or carbonyl inositol (PI) derivatives are found to be effective phospholipase C inhibitors which are useful anti-inflammatory and analgesic agents. Phospholipase C contained in mouse peritoneal macrophages has been linked to the enhanced turnover

Method of treating inflammation with inositol triphosphate

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FIELD OF THE INVENTION The present invention relates to a method of preventing or alleviating different conditions in the body by administering thereto a pharmaceutical composition comprising inositol triphosphate. BACKGROUND OF THE INVENTION Even as early as the year 1900, different researchers had

Synthetic analogues of phosphatidyl-myo-inositol mannosides with an inhibitory activity of the inflammatory response

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CROSS-REFERENCE TO RELATED APPLICATION This application is a National Stage entry of International Application No, PCT/FR2009/000595, filed May 20, 2009, which claims priority to French Patent Application No. 08/53357 filed May 23, 2008, the disclosure of the prior application is incorporated in its

Arginine silicate inositol complex and use thereof

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an arginine silicate inositol complex and its use in the prevention and treatment of a variety of disease states and disorders. 2. Description of the Related Art Until recently, infectious disease had been the

Carnitine and inositol phosphate-containing composition useful as dietary supplement or drug

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This application is a 371 of PCT/IT00/00158 filed Apr. 19, 2000. The present invention relates to a composition for the prevention and/or treatment of cardiovascular and neurocerebral disorders, various tissue anoxic forms, energetic muscular deficits, inflammatory type-abnormalities, blood

Tri-compound analgesic for treating inflammation and pain

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FIELD OF THE INVENTION This invention relates to analgesics, specifically to a method of controlling inflammation and pain. BACKGROUND OF THE INVENTION All early attempts at controlling pain were eventually superseded. Shortcomings of effectiveness and negative side effects were the reasons. This

Polyanion anti-inflammatory agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to the field of cell adhesion molecules and specifically to the use of inositol polyanion compositions for modulating selectin binding. 2. Description of Related Art Cell adhesion molecules (CAMs) play a role in

Phosphonates as anti-inflammation agents

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FIELD OF THE INVENTION This invention pertains to the synthesis and use as therapeutic agents of a group of substances with a glycerol backbone or aliphatic chain structure linked to phosphonocholine, phosphinocholine, phosphonoinositol, phosphinoinositol, or other phosphorus-containing head groups.

Inhibitors of human phosphatidyl-inositol 3-kinase delta

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FIELD OF THE INVENTION The present invention relates generally to phosphatidylinositol 3-kinase (PI3K) enzymes, and more particularly to selective inhibitors of PI3K activity and to methods of using such materials. BACKGROUND OF THE INVENTION Cell signaling via 3'-phosphorylated phosphoinositides

Certain chemical entities, compositions and methods

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BACKGROUND OF THE INVENTION The activity of cells can be regulated by external signals that stimulate or inhibit intracellular events. The process by which stimulatory or inhibitory signals are transmitted into and within a cell to elicit an intracellular response is referred to as signal

Methods and compositions for modulating T lymphocytes

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FIELD OF THE INVENTION The present invention generally relates to novel modulators of IP3K kinases and therapeutic applications of such modulators. More particularly, the invention pertains to novel IP3K modulators that modulate T lymphocyte differentiation and function, and to methods of using such

Antiinflammatory compositions and methods

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BACKGROUND OF THE INVENTION The present invention is concerned with an improved antiinflammatory composition and method of treating inflammation which employs a non-steroidal antiinflammatory agent such as piroxicam, or a pharmaceutically acceptable salt thereof (particularly the ethanolamine salt
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