neonatal sepsis/obesitat

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Effect of Maternal Obesity on Maternal-Fetal Transfer of Preoperative Cefazolin at Cesarean Section.

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OBJECTIVE American Congress of Obstetricians and Gynecologists recommends a single dose of antibiotic prophylaxis before all cesarean sections (C/S). This recommendation is based on pharmacokinetic studies that include only non-obese patients. We sought to evaluate 1) cefazolin plasma concentrations

Predictors of early-onset neonatal sepsis or death among newborns born at <32 weeks of gestation.

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To develop a predictive model for early-onset neonatal sepsis or death among infants born at less than 32 weeks of gestation.This was a case-control study of all deliveries <32 weeks between 2011 and 2015 in a single tertiary care center. Cases were

Maternal weight gain and neonatal outcomes in women with class III obesity.

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Objective: Obesity in the USA continues to be a prominent medical and public health concern. Due to increasing rates of maternal obesity, the current Institute of Medicine (IOM) guidelines recommend 11-20 pounds of total weight gain during pregnancy in women with a BMI ≥30 kg/m².

Impact of Maternal Obesity on Perinatal Outcomes in Preterm Prelabor Rupture of Membranes ≥34 Weeks.

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This study aimed to compare pregnancy outcomes in obese and nonobese women with preterm prelabor rupture of membranes (PPROM) ≥34 weeks.

STUDY DESIGN

The present study is a secondary analysis of a multicenter retrospective cohort of singletons with

Transcervical Foley Balloon Plus Vaginal Misoprostol versus Vaginal Misoprostol Alone for Cervical Ripening in Nulliparous Obese Women: A Multicenter, Randomized, Comparative-Effectiveness Trial.

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Nulliparous obese women are at increased risk of labor induction and cesarean delivery (CD). We sought to determine whether the combination of a transvaginal Foley balloon plus misoprostol prostaglandin E1 (PGE1) is superior to misoprostol alone in reducing the risk for

Diabetes during Pregnancy: Influence of Body Mass Index on Composite Morbidity.

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Objective This study aims to compare composite maternal and neonatal morbidities (MM, NM) among pregnant women with diabetes mellitus whose body mass index (BMI) at delivery was < 30 (group 1), 30.0 to 39.9 (group 2), and ≥ 40 kg/m 2 (group 3). We hypothesized that increased BMI class at delivery

What's new and novel in obstetric anesthesia? Contributions from the 2003 scientific literature.

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THE PREGNANT PATIENT: Age; maternal disease; prophylactic antibiotics; gastroesophageal reflux; obesity; starvation; genotyping; coagulopathy; infection; substance abuse; altered drug responses in pregnancy; physiological changes of pregnancy. THE FETUS: Fetal monitoring; intrauterine surgery. THE

S100A8 and S100A9 are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants

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Background & aims: After birth, the immune system matures via interactions with microbes in the gut. The S100 calcium binding proteins S100A8 and S100A9, and their extracellular complex form, S100A8-A9, are found in high amounts in

Gut microbiota, the immune system, and diet influence the neonatal gut-brain axis.

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The conceptual framework for a gut-brain axis has existed for decades. The Human Microbiome Project is responsible for establishing intestinal dysbiosis as a mediator of inflammatory bowel disease, obesity, and neurodevelopmental disorders in adults. Recent advances in metagenomics implicate gut

Perinatal antibiotic exposure of neonates in Canada and associated risk factors: a population-based study.

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OBJECTIVE To describe neonatal antibiotic exposures occurring immediately before and after birth and their associated risk factors. METHODS A retrospective review of the hospital charts of 449 mother-neonate pairs enrolled in the Canadian Healthy Infant Longitudinal Development national birth-cohort

Genetic and epigenetic factors and early life inflammation as predictors of neurodevelopmental outcomes

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Among individuals born very preterm, perinatal inflammation, particularly if sustained or recurring, is highly likely to contribute to adverse neurodevelopmental outcomes, including cerebral white matter damage, cerebral palsy, cognitive impairment, attention-deficit/hyperactivity disorder, and

Delivery for women with a previous cesarean: guidelines for clinical practice from the French College of Gynecologists and Obstetricians (CNGOF).

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The primary cause of uterine scars is a previous cesarean. In women with a previous cesarean, the risks of maternal complications are rare and similar after a trial of labor after cesarean (TOLAC) and after an elective repeat cesarean delivery (ERCD), but the risk of uterine rupture is higher with

Chorioamnionitis and intraamniotic infection.

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Intraamniotic infection is a common (2-4%) event in labor. The predictors of IAI include preterm labor or rupture of membranes, abnormal vaginal flora (e.g., GBS, sexually transmitted disease, bacterial vaginosis), obstetric manipulations (e.g., vaginal exams, internal fetal monitoring) in the

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