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[Prolonged fever and malignant schwannoma].

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Malignant peripheral nerve sheath tumor of the pancreas-A case report.

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Nerve sheath tumors are tumors arising from nerve sheaths or which show nerve sheath differentiation. They are divided as benign and malignant. They are associated with Von Recklinghausen syndrome. Characterised by café-au-lait spots, lisch nodules, acoustic neuromas,

Can we differentiate malignant peripheral nerve sheath tumor from benign neurofibroma without invasive sampling.

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One of the most important benign tumors in neurofibromatosis type 1 (NF1) is plexiform neurofibroma, and there is a risk of developing malignant peripheral nerve sheath tumor (MPNST) throughout life approximately 10%. However lesion characterization by anatomical imaging methods are not possible.

[Mediastinal malignant schwannoma in a patient without Von Recklinghausen disease].

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Malignant tumors of peripheral nerve sheath (malignant Schwannoma) arising in mediastinum are rare, principally in patients without Von Recklinghausen's disease been fever exceptional as symptom of presentation. We present a case of a woman without neurofibromatosis with a malignant Schwannoma in

A Phase II Trial of Sorafenib and Dacarbazine for Leiomyosarcoma, Synovial Sarcoma, and Malignant Peripheral Nerve Sheath Tumors.

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BACKGROUND Sorafenib and dacarbazine have low single-agent response rates in metastatic sarcomas. As angiogenesis inhibitors can enhance the efficacy of chemotherapy, we investigated the combination of sorafenib and dacarbazine in select sarcoma subtypes. METHODS Patients with leiomyosarcoma (LMS),

Radio frequency hyperthermia of advanced human sarcomas.

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Hyperthermia greater than or equal to 42 degrees C is tumoricidal in vitro and in many animal models, although such temperatures have only recently been achieved experimentally in some human cancers. A recently developed radio frequency device that provides safe hyperthermia to any depth without

Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas.

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One hundred and forty adult patients with advanced sarcomas (125 soft tissue and 15 bone) were treated with a combination chemotherapy regimen consisting of cyclophosphamide, vincristine, Adriamycin, and DTIC (CYVADIC). There were 21 (15%) complete and 45 (32%) partial responders, with an overall

Interleukin-6 immunoreactivity in human tumors.

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The cytokine, interleukin-6 (IL-6), has emerged as a likely mediator of many of the systemic alterations observed in patients with cancer (fever, increased erythrocyte sedimentation rate, and alterations in plasma protein composition) and may also mediate local effects such as alteration in

[Primary pulmonary schwannoma: clinical analysis of 7 cases and review of the literature].

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OBJECTIVE To analyze the clinical and radiological manifestations of primary pulmonary schwannoma in order to improve the diagnosis of this rare disease. METHODS Seven cases of primary pulmonary schwannoma which was confirmed by pathology of surgical specimens were retrospectively

Multiple neurofibromas plus fibrosarcoma with familial NF1 pathogenicity: A case report.

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Neurofibromatosis (NF) is a genetic disease consisting of seven types, of which types 1 to 4 are caused by a dominant autosomal gene mutation; such disease sometimes arises in patients with NF type 1. However, it remains unclear whether the origin of neurofibrosarcoma is directly

Phase II evaluation of doxorubicin for treatment of various canine neoplasms.

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One hundred eighty-five dogs with histologically confirmed, measurable malignant tumors were used in a prospective study to determine the response to 2 doses of the anthracycline antitumor antibiotic, doxorubicin. Eighty-three dogs had been refractory to one or more previous treatment modalities

The IVADo regimen--a pilot study with ifosfamide, vincristine, actinomycin D, and doxorubicin in children with metastatic soft tissue sarcoma: a pilot study of behalf of the European pediatric Soft tissue sarcoma Study Group.

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BACKGROUND The role of doxorubicin (Doxo) as part of multidrug regimens used to treat children with soft tissue sarcoma (STS) is controversial. To evaluate the feasibility of combining Doxo with the well established ifosfamide, vincristine, and actinomycin D (IVA) regimen, the Italian STS Committee

Mediastinal malignant triton tumor: A rare case series and review of literature.

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In 1938, the Malignant Triton Tumor (MTT) was first explained by Mason.Case 1: A man aged 28 years presented with chest pain and difficulty in breathing since last five months, there was no history of cough fever or night sweats. Clinical examination was

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