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High prevalence of malaria parasitemia and anemia among hospitalized children in Rakai, Uganda.

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BACKGROUND There is a paucity of data on malaria among hospitalized children in malaria endemic areas. We determined the prevalence, presentation and treatment outcomes of malaria and anemia among children in two hospitals in Rakai, Uganda. METHODS Children under five years hospitalized in Kalisizo

[A case of mefloquine-resistant Plasmodium falciparum malaria with convulsion after antimalarial treatment].

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We report a case of 40-year-old with chloroquine- and mefloquine-resistant Plasmodium falciparum. He had a single grand mal seizure 37 days following retreatment with quinine intravenously, which resulted in rapid clearance of fever and parasitemia, in addition to mefloquine. He had a long history

Estradiol, but not dehydroepiandrosterone, decreases parasitemia and increases the incidence of cerebral malaria and the mortality in plasmodium berghei ANKA-infected CBA mice.

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OBJECTIVE The effect of castration and subsequent replacement of dehydroepiandrosterone (DHEA) or estradiol on parasitemia, mortality and incidence of cerebral malaria (CM) was evaluated in CBA mice infected with Plasmodium berghei ANKA. METHODS Female mice were castrated, and groups of 12-15

[Parasitemia in Plasmodium falciparum malarial attacks in children].

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In order to evaluate the predictive value of parasitaemia, this parameter was measured on admission in 69 Gabonese children aged from 3 to 13 years hospitalized for Plasmodium falciparum malarial attacks. Fourteen of these children had cerebral malaria, 5 had isolated convulsions and 50 had

[Severe forms of malaria in children in a general hospital pediatric department in Yaounde, Cameroon].

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Severe forms of malaria in children are responsible for 1 million deaths yearly in young children in hyperendemic areas. The main objective of this study was to identify and compare common manifestations of different forms of severe malaria and to evaluate the prognosis for hospital treatment in an

[Congenital toxoplasmosis].

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BACKGROUND Toxoplasma gondii is a ubiquitous parasite of all species of mammals and birds (1). Most often the infection in the immunocompetent persons is asymptomatic. Symptoms (if present) are usually mild and self-limited. Infection in the fetus and immunodeficient patients may lead up to

Effects of DNA vaccine in murine malaria using a full-length cDNA library.

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In an attempt to develop a novel malaria vaccine, we constructed a full-length cDNA library from the erythrocytic-stage parasites of Plasmodium berghei ANKA strain using the plasmid vector pCE-FL, which is driven by an EF321 promoter and a CMV-IE enhancer. Here we report the initial trial to screen

Postmalaria neurological syndrome after treatment of Plasmodium falciparum malaria in the United States.

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The neuropsychiatric manifestations of postmalaria neurological syndrome (PMNS) that have been described are highly variable and include an acute confusional state or acute psychosis with >or=1 of the following symptoms: clouding of consciousness, inappropriate speech or behavior, visual

[Case management and diagnosis of severe malaria in adults and the application of national guidelines in Burkina Faso].

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The purpose of this study was to assess the application of national guidelines on the diagnosis and treatment of severe malaria in adults in Burkina Faso. We conducted a retrospective study of medical records of the patients admitted for severe malaria in the emergency service of the regional

Predictors of acute bacterial meningitis in children from a malaria-endemic area of Papua New Guinea.

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Predictors of acute bacterial meningitis (ABM) were assessed in 554 children in Papua New Guinea 0.2-10 years of age who were hospitalized with culture-proven meningitis, probable meningitis, or non-meningitic illness investigated by lumbar puncture. Forty-seven (8.5%) had proven meningitis and 36

Cerebral malaria in children.

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A retrospective chart review for the 1993 calendar year identified 187 children with cerebral malaria admitted to a large teaching hospital in central Ghana, West Africa. The most common clinical presentation was fever, sensorial depression and convulsions in young children experiencing their first

[Cerebral malaria in the child. A study of 11 cases with good prognosis at CHU of Yaoundé, Cameroon].

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From January to December 1993, 11 cases of cerebral malaria out of a total of 106 cases of malaria were admitted in the paediatric unit of the Yaounde University Teaching Hospital. These 11 patients were comprised of 6 boys and 5 girls aged 6 months to 10 years with a mean of 4.24 years. Convulsions

Increased synapsin I expression in cerebral malaria.

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Synapsin I is a neuronal phosphoprotein contained in the synaptic vesicles of mammalian central and peripheral nervous systems. It regulates both neurotransmitter release and synaptic formation. Variations in synapsin I expression in the brain have been reported to cause brain malfunction. In severe

[Diluted injectable quinine in the intramuscular and intrarectal route: comparative efficacity and tolerance in malaria treatment for children ].

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The intramuscular (i.m.) route is generally used for treatment of childhood falciparum malaria in outlying health care units in Togo. The purpose of this randomized therapeutic trial was to compare the efficacy and tolerance of diluted injectable quinine administered by the i.m. versus intrarectal

Childhood malaria in East London.

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OBJECTIVE To describe the epidemiologic, clinical and laboratory features of children younger than 16 years with malaria in East London. METHODS Retrospective case review of all children admitted to two East London hospitals with malaria identified between 1996 and 2001 with the use of notifications

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