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14 resultats
COlchicine in Moderate-severe Hospitalized Patients Before ARDS to Treat COVID-19
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Prospective, completely randomized, open labeled, controlled study. Patients will be randomized into two groups (A and B). Patients of group A will be treated under what is considered current standard of care at Maimonides Medical Center while group B patients will receive colchicine in addition to
Evaluation of Effect of Topical Melatonin in Treatment of Oral Leukoplakia
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The World Health Organization (W.H.O). defines oral potentially malignant disorders (OPMDs) as "A histologically proven lesion that is associated with a significantly increased risk of malignant transformation."Oral leukoplakia is the most commonly occurring oral potentially malignant disorder.
Simvastatin in Secondary Progressive Multiple Sclerosis
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Approximately 60% of those affected with relapsing-remitting MS (RRMS) enter a SPMS stage after a median interval of 10 to 15 years, where disability accumulates gradually in the absence of relapses. A smaller proportion (15%), run a progressive course from onset (primary progressive (PP) MS). The
Effect of Dietary Nitrate Ingestion in Heart Failure
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Background: Heart failure (HF) affects 1-2% of those under 70 years, and 10-20% of those over 70 years in developed countries; approximately 900,000 people in the UK suffer with HF. Despite several promising pre-clinical targets, clinical translation has been disappointing, with very few successful
The Beneficial Effects of Pomegranate on Hearing of Patients Without Hemodialysis
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Pomegranate has anti-oxidative capacity. It might reduce symptoms of Alzheimer's disease, Drug-induced hepatitis, and might prevent deterioration of cardiovascular diseases and cancer progression. But, the beneficial effects of pomegranate on hearing impairment was still unclear.
This study aimed to
Efficacy of Prunus Domestica Extract in BPH
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Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate. Symptoms related to BPH are one of the most common problems in older men. Histological evidence of BPH is found in more than is approximately 10% for men in their 30s, 20% for men in their 40s, reaches 50% to 60% for
Community Hospital Identification of High CV Risk Patients During Cancer Treatment
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While recent research indicates that conventional MRI, advanced echocardiography (global longitudinal strain and 3D) and serum biomarkers can detect CV injury early after receipt of Chemotherapy, these methods require lengthy and difficult examinations that are not routinely executed in community
Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling
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1. Specific Aims There is general agreement that although statin-treatment increases incidence of type 2 diabetes (T2DM) in patients with elevated plasma low-density lipoprotein cholesterol (LDL-C) concentrations, the benefits of statin treatment significantly outweigh this untoward side-effect.
Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study
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Protocol Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study
Introduction Multiple sclerosis (MS) is characterized pathologically by demyelination, axonal loss, and glial scar formation. Clinically, most patients have a relapsing-remitting course of MS (RRMS)
12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled Study
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This 12 month double-blind, randomized, placebo-controlled, parallel group efficacy and safety study will enroll 400 adult diabetic subjects with diabetic peripheral neuropathy (DPN) to investigate the effect of diepalrestat (BNV-222) 150 mg, 300 mg, or placebo on MNCV and patients' perception of
Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy
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Statins, a class of hydroxyl methylglutaryl-coenzyme A reductase inhibitors that lower low-density lipoprotein cholesterol, are commonly prescribed to patients with the metabolic syndrome or those with multiple cardiovascular disease risk factors when lifestyle changes fail to achieve LDL targets to
Combination of Hydroxyurea and Verapamil for Refractory Meningiomas
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The investigators have demonstrated previously that the calcium channel antagonists (CCAs) verapamil, nifedipine, and diltiazem can block in vitro and in vivo meningioma growth at clinically relevant doses (Jensen, Lee et al. 1995; Jensen, Petr et al. 2000; Jensen and Wurster 2001). However, only
Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)
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Background:
Spinal and bulbar muscular atrophy (SBMA) or Kennedy's disease is a slowly progressive, X-linked motor neuron disease for which there is currently no treatment. It is caused by a mutation in the androgen receptor that results in a polyglutamine repeat expansion. Recent animal studies
Self-management for Men With Uncomplicated Lower Urinary Tract Symptoms
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1. OBJECTIVES
To assess the effectiveness of self-management interventions in men with uncomplicated LUTS.
2. STUDY DESIGN
2.1 This is a randomised controlled trial comparing self-management with standard therapy. These interventions are proposed to optimise watchful waiting, providing an
La base de dades d’herbes medicinals més completa avalada per la ciència
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- Cures a base d'herbes recolzades per la ciència
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- Llegiu publicacions científiques relacionades amb la vostra cerca
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* Tota la informació es basa en investigacions científiques publicades
