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Pàgina 1 des de 16 resultats
Methods and compositions for regulation of 5-.alpha.-reductase activity
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TECHNICAL FIELD OF THE INVENTION
The present invention relates generally to compounds, compositions methods regulating the action and function of androgens and other steroid hormones by modulating the activity of steroid-reductases, including isozymes of 5.alpha.-reductases. More specifically, the
Controlled release complex composition comprising angiotensin-II-receptor blockers and HMG-CoA reductase inhibitors
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a 35 U.S.C. .sctn.371 National Phase Entry Application from PCT/KR2007/005405, filed Oct. 30, 2007, and designating the United States, which claims priority under 35 U.S.C. .sctn.119 to Korean Patent Application No. 10-2006-0105617 filed
Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses
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BACKGROUND OF THE INVENTION
The present invention relates to a series of compounds which are characterised by a 2-[2-(substituted phenyl-oxy, thio or methyl)-1-methylethyl]aminoethanol structure and which have valuable anti-diabetic and anti-obesity activities; in addition, they are capable of
Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses
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BACKGROUND TO THE INVENTION
The present invention relates to a series of compounds which are characterised by a 2-[2-(substituted phenyl-oxy, thio or methyl)-1-methylethyl]aminoethanol structure and which have valuable anti-diabetic and anti-obesity activities; in addition, they are capable of
Methods for decreasing beta amyloid protein
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BACKGROUND OF THE INVENTION
Alzheimer's disease (AD) is the most common cause of dementia in the aged population. The accumulation of large numbers of senile plaques containing the 40-42 amino acid amyloid .beta. protein (A.beta.) is a classic pathological feature of AD. Both genetic and cell
Methods for determining risk of Alzheimer's disease
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BACKGROUND OF THE INVENTION
The United States government has certain rights in this invention by virtue of National Institutes of Health grant number RO1NS33325 to Bruce A. Yankner.
Alzheimer's disease (AD) is the most common cause of dementia in the aged population. The accumulation of large
Oxime derivatives, their preparation and their therapeutic use
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BACKGROUND TO THE INVENTION
The present invention relates to a series of new oxime derivatives which contain inter alia, a thiazolidinedione or oxazolidinedione group attached, via a methylene or methylidene group, to a benzene ring and which have a variety of therapeutic uses, and provides
Oxime derivatives, their preparation and their therapeutic use
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BACKGROUND OF THE INVENTION
The present invention relates to a series of new oxime derivatives which contain inter alia, a thiazolidinedione or oxazolidinedione group attached, via a methylene or methylidene group, to a benzene ring and which have a variety of therapeutic uses, and provides
Oxime derivatives, their preparation and their therapeutic use
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BACKGROUND OF THE INVENTION
The present invention relates to a series of new oxime derivatives which contain inter alia, a thiazolidinedione or oxazolidinedione group attached, via a methylene or methylidene group, to a benzene ring and which have a variety of therapeutic uses, and provides
Method for stimulating AMP-activated protein kinase
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BACKGROUND OF THE INVENTION
Guggul is a type of myrrh derived from Commiphora mukul, a small tree of the Bursaceae family native to India. Pakistan and Bangladesh. The gum resin (guggul) has been traditionally used in Ayurveda for its hypolipidemic, hypocholesterolemic, anticancer, anti-diabetic and
Apo B-secretion/MTP inhibitory amides
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FIELD OF THE INVENTION
This invention relates to compounds which are inhibitors of microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (Apo B) secretion and which are, accordingly, useful for the prevention and treatment of atherosclerosis and its clinical sequelae, for lowering
CETP inhibitors in combination with antihypertensive agents and uses thereof
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BACKGROUND OF THE INVENTION
This invention relates to pharmaceutical combinations of a cholesteryl ester transfer protein (CETP) inhibitor or a pharmaceutically acceptable salt thereof; and an antihypertensive agent or a pharmaceutically acceptable salt thereof, optionally in combination with an HMG
Combination therapeutic compositions
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FIELD OF INVENTION
In general, the present invention relates to pharmaceutical compositions, and more particularly, to pharmaceutical compositions for the treatment of diabetes mellitus using combination therapy.
BACKGROUND OF THE INVENTION
Diabetes mellitus is a term generally used to refer to
Combination therapeutic compositions and method of use
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FIELD OF INVENTION
In general, the present invention relates to pharmaceutical compositions, and more particularly, to pharmaceutical compositions for the treatment of diabetes mellitus using combination therapy.
BACKGROUND OF THE INVENTION
Diabetes mellitus is a term generally used to refer to
Combination therapeutic compositions and method of use
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FIELD OF INVENTION
In general, the present invention relates to pharmaceutical compositions, and more particularly, to pharmaceutical compositions for the treatment of diabetes mellitus using combination therapy.
BACKGROUND OF THE INVENTION
Diabetes mellitus is a term generally used to refer to
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* Tota la informació es basa en investigacions científiques publicades
