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Pàgina 1 des de 44 resultats
Chronic corticosterone-induced deterioration in rat behaviour is not paralleled by changes in hippocampal NF-kappaB-activation.
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We investigated whether long-lasting stress induced by chronic glucocorticoid (GC) exposure affects activation of brain NF-kappaB and whether these changes are related to functional deterioration and structural changes in the rat hippocampus. Psychometric investigations were conducted using a
Soleus muscle atrophy in rats induced by cast immobilization: lack of effect by anabolic steroids.
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To test the hypothesis that an anabolic steroid such as nandrolone decanoate (ND) will ameliorate or abolish disuse-mediated alterations resulting from five weeks of hindlimb immobilization, female Sprague-Dawley rats were divided into six groups: control, control + ND, shortened-immobilized,
Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats.
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Melatonin is an endogenously generated potent antioxidant. Our previous studies indicate that melatonin improved learning and memory deficits in APP695 transgenic mouse of Alzheimer's disease. An ovariectomized (OVX) rat model which is characterized by progressive memory deficits, central
Investigation of the hepatoprotective effects of Sesame (Sesamum indicum L.) in carbon tetrachloride-induced liver toxicity.
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More than 600 chemicals can cause damage in liver, one of which is carbon tetrachloride (CCl₄). Hepatoprotective agents could prevent tissue damage and reduce morbidity and mortality rates; such agents may include alternative or folkloric treatments. We investigated sesame (Sesamum indicum L.) for
Integrated approach for disease management and growth enhancement of Sesamum indicum L. utilizing Azotobacter chroococcum TRA2 and chemical fertilizer.
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Azotobacter chroococcum TRA2, an isolate of wheat rhizosphere displayed plant growth promoting attributes including indole acetic acid, HCN, siderophore production, solubilization of inorganic phosphate and fixation of atmospheric nitrogen. In addition, it showed strong antagonistic effect against
Progesterone promotes oocyte maturation, but not ovulation, in nonhuman primate follicles without a gonadotropin surge.
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During the periovulatory interval, intrafollicular progesterone (P) prevents follicular atresia and promotes ovulation. Whether P influences oocyte quality or maturation and follicle rupture independent of the midcycle gonadotropin surge was examined. Rhesus monkeys underwent controlled ovarian
The toxicity of brominated sesame oil and brominated soybean oil in miniature swine.
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Miniature swine were fed brominated sesame oil at dietary levels of 0, 5, 25, 50 or 500 mg/kg of body weight for 17 weeks and brominated soybean oil at levels of 0, 5, 50 or 500 mg/kg of body weight for 28 weeks. Growth rate and food intake were decreased only at the high dose level in the
The Selective Glucocorticoid Receptor Modulator Cort 113176 Reduces Neurodegeneration and Neuroinflammation in Wobbler Mice Spinal Cord.
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Wobbler mice are experimental models for amyotrophic lateral sclerosis. As such they show motoneuron degeneration, motor deficits, and astrogliosis and microgliosis of the spinal cord. Additionally, Wobbler mice show increased plasma, spinal cord and brain corticosterone levels and focal
Administration of testosterone fails to attenuate axotomy-induced motoneuron loss but results in castration-like effect in young male rats.
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It was shown previously that the severity of motoneuron loss induced by nerve transection in rats 3 or 6 weeks of age was correlated inversely with the level of testosterone in circulation [Yu, W.H.A., Exp. Neurol. 102: 230-235, 1988], and that administration of testosterone to female rats
Management of muscular dystrophy during osteoarthritis disorder: A topical phytotherapeutic treatment protocol.
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Antihypertensive effect of sesamin. III. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats.
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The antihypertensive effect of sesamin, a lignan from sesame oil, was examined using salt-loaded and unloaded stroke-prone spontaneously hypertensive rats (SHRSP). The animals at 6 weeks of age were separated into a salt-loaded group and an unloaded group. Salt-loaded animals were maintained on 1%
Sesame lignans suppress age-related disorders of the kidney in mice
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Objective: Sesamin is a functional ingredient in sesame (Sesamum indicum) seeds and has many physiological effects. This study investigated whether sesame lignans, sesamin and episesamin (1:1), can suppress age-related disorders of the
FURTHER STUDIES IN EXPERIMENTAL ATHEROSCLEROSIS.
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Cholesterol dissolved in sesame oil and injected regularly for a period of from 7 to 8 months into the jugular vein of four young dogs has caused in each animal larger and smaller nodules protruding to some degree into the lumen of the pulmonary artery and also here and there some diffuse
Molecular characterization and interviral homologies of a potyvirus infecting sesame (Sesamum indicum) in Georgia.
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Phylogenetic analyses of the 3' terminal region of a potyvirus naturally infecting sesame (Sesamum indicum) in Georgia indicated that the virus belongs to the passionfruit woodiness potyvirus subgroup, and is most closely related to cowpea aphid-borne mosaic potyvirus (CABMV) and South African
The protective effects of omega 3 fatty acids and sesame oil against cyclosporine A-induced nephrotoxicity.
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Cyclosporine A (CsA) is a drug used in autoimmune disorders and organ transplantations. Omega 3 fatty acids (O-3) and sesame oil (SO) have antioxidant properties. We aimed to investigate and compare the protective effects of O-3 and SO against CsA-induced nephrotoxicity. Seven groups of male Wistar
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