daily dose of 1000 mg vitamin c in order to regenerate collagen

Spinal manipulation in cervical and dorsal with high speed and short amplitude techniques

manual muscle treatment for epicondyl musculature

Lateral Epicondylitis

Tennis Elbow

Will apply 1000mg of vitamin C, TENS and manual therapy. One session will be held per week for 6 weeks.

Vitamin C

Applied spinal manipulations, tens and manual therapy.One session will be held per week for 6 weeks.

spinal manipulation

Received a manual therapy intervention and Tens. one session will be held per week for 6 weeks.

Transcutaneous electrical nerve stimulation (TENS)

Pablo Federico Scillone Tessore

Efficacy of Vitamin C Supplement vs Spinal Manipulation to Treatment in Lateral Epicondylitis

Efficacy of Vitamin C Supplement Addiction vs. High-speed Spinal Manipulation to Routine Physiotherapy Treatment in Lateral Epicondylitis

For this, patients will be indicated how they should complete the scale, providing a numerical value from 0 to 10, being 10 0 no pain, and 10 the most severe or intense pain. The numerical pain scale is a simple, solid, sensitive and reproducible instrument, useful for reassessing patient pain

The questionnaire will consist of 30 questions about their symptoms and the ability to carry out certain activities and has been validated in Spanish. The patient should answer the questions by circling the number that best describes their condition during the past week. Each item will be answered on a scale from 1 to 5, where 1 indicates that it has no difficulty executing, has no symptoms or impact, and 5 indicates that it cannot be performed, that it has very severe symptoms and a strong impact.

The 15-point improvement self-perception scale (GROC) will be used, consisting of a 15-point Likert scale ranging from a rating of 0 to +7 (I am much better) or -7 (I am much worse).
eleven The descriptors of improvement range from +1 to +7, and those of worsening from -1 to -7. A value of +5 has been shown to be indicative of moderate clinical improvement, while a value of +6 or +7 suggests high clinical improvement.

Pressure pain threshold will be analyzed, defined as the minimum amount of pressure applied to produce pain

Principal Investigator

Universidad Rey Juan Carlos

Inflammatory Back Pain

The investigators will evaluate the effect of a gluten free diet (GFD) in IBP patients, randomly assigned to receive standard therapy for IBP or standard therapy for IBP plus GFD, for a period of at least one year.

Gluten free diet

Department of Internal Medicine, Giovanni Paolo II Hospital of Sciacca

Department of Internal Medicine, University Hospital of Palermo

Inflammatory Back Pain and Gluten Free Diet

Musculoskeletal (back pain) evaluation, from baseline at 12 months of GFD, according to the scores calculated on the basis of Visual Analogue Scales for Musculoskeletal (back pain), taking into account whether the patients adhered or not to the GFD.

Changes in cytokines production from peripheral blood mononuclear (PBMC), from baseline (i.e. at diagnosis) at 12 months of GFD, taking into account whether the patients adhered or not to the GFD.

Prevalence of IBP in CD and in NCWS patients.

Pasquale Mansueto

University of Palermo

Patients receive levofloxacin PO or IV over 60-90 minutes once or twice daily beginning on day 3 during 2 consecutive courses of chemotherapy or beginning on day -2 during HSCT and continuing until blood counts recover.

Patients receive established standard of care and receive chemotherapy or HSCT as patients in Arm I.

Patients receive levofloxacin PO or IV over 60-90 minutes once or twice daily beginning on day 3 during 2 consecutive courses of chemotherapy or beginning on day -2 during HSCT and continuing until blood counts recover.
levofloxacin: Given PO or IV

Arm I (Levofloxacin)

Arm II (Standard of Care)

Total

Sex: Female, Male

Ethnicity (NIH/OMB)

Race (NIH/OMB)

Region of Enrollment

A bacteremia incidence is defined as an occurrence of at least 1 episode of true (centrally reviewed) bacteremia among Acute Leukemia (AL) and Hematopoietic stem cell transplantation (HSCT) patients.

Comparison of the Percentage of Patients Having Bacteremia Incidence Between Levofloxacin vs. No Prophylaxis Arms

Exposure to antibiotics was considered during the infection observation period(s) was defined a priori as follows: Gram positive agents = vancomycin, linezolid, daptomycin or quinupristin/dalfopristin; Aminoglycosides = amikacin, gentamicin or tobramycin; Third or fourth generation cephalosporins = cefepime, ceftazidime, ceftriaxone or cefotaxime; Empiric antibiotics for fever and neutropenia = imipenem, meropenem, cefepime, ceftazidime or piperacillin/tazobactam

Comparison of the Percentage of Patients Having Antibiotic Exposures Between Arms

Fever and febrile neutropenia defined as Absolute Neutrophil Count (ANC) < 1000/mm3 with a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >= 38 degrees C (100.4 degrees F) for more than one hour.

Comparison of the Percentage of Patients Having Incidence of Fever and Febrile Neutropenia Between Arms

Severe infection defined as any grade 4 or 5 CTCAE catheter-related infection, enterocolitis, lung infection, sepsis, small intestine infection and other infections or infestations

Comparison of the Percentage of Patients Having Severe Infection Between Arms

Comparison of the Percentage of Patients That Died Due to Bacterial Infection Between Arms

Musculoskeletal conditions included at least one occurrence of arthralgia, arthritis, gait abnormality or tendinopathy.

Comparison of the Percentage of Patients Having Incidence of Musculoskeletal Adverse Events Including Tendinopathy (Tendonitis and Tendon Rupture) Between Arms

Clostridium Difficile Associated Disease (CDAD) is defined as a positive C. difficile toxin assay result and diarrhea, CTCAE version 4, grade 2 and higher.

Comparison of the Percentage of Patients Having Incidence of CDAD Between Arms

Overall Study

Results Reporting Coordinator

Acute Leukemias of Ambiguous Lineage

Bacterial Infection

Diarrhea

Fungal Infection

Musculoskeletal Complications

Neutropenia

Recurrent Childhood Acute Lymphoblastic Leukemia

Recurrent Childhood Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies

levofloxacin

Arkansas Children's Hospital

Southern California Permanente Medical Group

City of Hope Medical Center

Loma Linda University Medical Center

Miller Children's Hospital

Children's Hospital Los Angeles

Cedars-Sinai Medical Center

Rady Children's Hospital - San Diego

University of California San Francisco Medical Center-Parnassus

Connecticut Children's Medical Center

Alfred I duPont Hospital for Children

Children's National Medical Center

Lombardi Comprehensive Cancer Center at Georgetown University

Golisano Children's Hospital of Southwest Florida

Nemours Children's Clinic - Jacksonville

Nemours Children's Hospital

Nemours Children's Clinic - Pensacola

All Children's Hospital

Saint Mary's Hospital

Children's Healthcare of Atlanta - Egleston

Georgia Regents University

University of Illinois

Advocate Children's Hospital-Oak Lawn

Riley Hospital for Children

Saint Vincent Hospital and Health Services

Blank Children's Hospital

University of Kentucky

Kosair Children's Hospital

Tulane University Health Sciences Center

Children's Hospital-Main Campus

Ochsner Medical Center

Sinai Hospital of Baltimore

Floating Hospital for Children at Tufts Medical Center

Dana-Farber Cancer Institute

C S Mott Children's Hospital

Helen DeVos Children's Hospital at Spectrum Health

Michigan State University - Breslin Cancer Center

Children's Hospitals and Clinics of Minnesota - Minneapolis

University of Mississippi Medical Center

Saint John's Mercy Medical Center

Children's Hospital and Medical Center of Omaha

University of Nebraska Medical Center

Nevada Cancer Research Foundation CCOP

Hackensack University Medical Center

Saint Peter's University Hospital

UMDNJ - Robert Wood Johnson University Hospital

University of New Mexico Cancer Center

Montefiore Medical Center

Roswell Park Cancer Institute

New York University Langone Medical Center

Columbia University Medical Center

University of Rochester

Ny Cancer%

Mission Hospital-Memorial Campus

Wake Forest University Health Sciences

Children's Hospital Medical Center of Akron

Cleveland Clinic Foundation

Nationwide Children's Hospital

The Children's Medical Center of Dayton

The Toledo Hospital/Toledo Children's Hospital

University of Oklahoma Health Sciences Center

Lehigh Valley Hospital - Muhlenberg

Geisinger Medical Center

Children's Hospital of Philadelphia

Children's Hospital of Pittsburgh of UPMC

Palmetto Health Richland

Sanford USD Medical Center - Sioux Falls

Driscoll Children's Hospital

University of Texas Southwestern Medical Center

Brooke Army Medical Center

Cook Children's Medical Center

Baylor College of Medicine

University of Texas Health Science Center at San Antonio

Methodist Children's Hospital of South Texas

Childrens Hospital-King's Daughters

Providence Sacred Heart Medical Center and Children's Hospital

Madigan Army Medical Center

Marshfield Clinic

CancerCare Manitoba

Janeway Child Health Centre

McMaster Children's Hospital at Hamilton Health Sciences

Cancer Centre of Southeastern Ontario at Kingston General Hospital

Hospital for Sick Children

The Montreal Children's Hospital of the MUHC

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

Children's Oncology Group

National Cancer Institute (NCI)

Abscess

Cysts

cefpirome and moxifloxacin administration

Medical University Vienna

Plasma and Abscess Fluid Pharmacokinetics of Cefpirome and Moxifloxacin After Single and Multiple Dose Administration

tendinopathy/diarrea

Efficacy of Vitamin C Supplement vs Spinal Manipulation to Treatment in Lateral Epicondylitis

Inflammatory Back Pain and Gluten Free Diet

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Plasma and Abscess Fluid Pharmacokinetics of Cefpirome and Moxifloxacin After Single and Multiple Dose Administration

La base de dades d’herbes medicinals més completa avalada per la ciència