tendinopathy/diarrea

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Achilles tendinitis as a rare extraintestinal manifestation of ulcerative colitis.

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Patients with inflammatory bowel disease often have extraintestinal manifestations (EIMs) involving almost all organ systems, but little has been reported on Achilles tendinitis. Herein, we present a unique case of Achilles tendinitis, which manifested shortly after initiation of mesalazine therapy

Fluoroquinolone-induced tendinopathy: etiology and preventive measures.

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Tendinopathy is a serious health problem and its etiology is not fully elucidated. Among intrinsic and extrinsic predisposing factors of tendinopathy, the impact of therapeutic agents, especially fluoroquinolone (FQ) group antibiotics, is recently being recognized. FQs are potent bactericidal agents

[Reiter's disease following salmonella infection in an HL-A-B27 carrier].

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Reiter's syndrome following salmonella enteritidis (Gärtner) infection in an HLA-B27 carrier is described. Some weeks after an episode of fever and diarrhea, a 33-year-old male presented with sacroiliitis, Achilles tendinitis and aphthous stomatitis. During the next few months he developed chronic

Safety concerns with fluoroquinolones.

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OBJECTIVE To review the chemistry, pharmacology, and safety of fluoroquinolones. METHODS A MEDLINE search (1966-July 2007) was conducted using the key words fluoroquinolones or quinolones with safety, adverse effects, hypoglycemia, hyperglycemia, dysglycemia, QTc prolongation, torsades, seizures,

Gender differences among long-distance backpackers: A prospective study of women Appalachian Trail backpackers.

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OBJECTIVE Backpacking is a popular recreational activity, yet the differential experiences of women are unknown. The objective was to compare women with men backpackers to determine the extent to which injuries and illnesses limit endurance outdoor recreational activities. METHODS This was a

[Diclofenac-induced colitis complicated by Klebsiella oxytoca infection].

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A 25-year-old man presented with abdominal pain and bloody diarrhea. Colonoscopy showed hemorrhagic proctocolitis with superficial erosions. Histology was consistent with the diagnosis of ulcerative colitis and biopsy cultures were negative. Despite treatment with prednisolone (40 mg/day), his

A prospective study of patients with spondyloarthropathy with special reference to HLA-B27 and to gut histology.

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Ileocolonoscopy was performed on 357 patients meeting the European Spondylarthropathy Study Group criteria for spondyloarthropathy. HLA loci A, B and C were determined in all patients; HLA-B27 was detected in 196 and was absent in the 161 remaining patients. A number of clinical, laboratory and

[Toxicity of quinolone antibiotics - new untoward effects and reevaluation of known side effects].

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Quinolones have recently been reevaluated based on new possible side effects and new risk assessments of known side effects. Several of the recently reported untoward effects are not new to the class, and they are very rare compared with the relatively common neuropsychiatric adverse events. New

Close association of herpes zoster reactivation and systemic lupus erythematosus (SLE) diagnosis: case-control study of patients with SLE or noninflammatory nusculoskeletal disorders.

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To investigate the prevalence of infections, particularly the frequency of shingles and the timing of varicella zoster virus (VZV) reactivation, and antibiotic use, vaccinations, and joint trauma prior to and at diagnosis of systemic lupus erythematosus (SLE). We sent questionnaires to patients with

Infections are not increased in scleroderma compared to non-inflammatory musculoskeletal disorders prior to disease onset.

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The etiology of scleroderma (SSc) is unknown; immunogenic stimuli such as infections and vaccinations could theoretically be risk factors for scleroderma. Our objective was to assess the relationship between viral and bacterial infections, and vaccinations, prior to diagnosis of SSc compared to

Levofloxacin-induced tactile hallucination and acute anxiety reaction.

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Fluoroquinolones are the commonly used antimicrobials in the treatment of urinary tract infection, bacterial diarrhea, and infections of soft tissue, bone, and joints. They may cause adverse effects ranging from gastrointestinal disturbances, headache, insomnia, and cutaneous reactions. Their rare

Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study.

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OBJECTIVE Uncomplicated pelvic inflammatory disease (PID) is a common disease caused by numerous pathogens: sexually transmitted infections (such as Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium), anaerobes, and other organisms from the vaginal flora. It is currently treated

[Tolerability and safety of levofloxacinin long-term treatment].

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Levofloxacin is a useful quinolone for patients infected with osteomyelitis or tuberculosis. There is little information on the tolerance and safety of levofloxacin in long-term treatment. Fifteen patients (10 men and 5 women) with prosthetic joint infection or chronic osteomyelitis were analyzed.

Risks associated with the therapeutic use of fluoroquinolones.

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BACKGROUND Quinolones are among the most often prescribed antimicrobial agents. Some types of toxicity observed during therapy with these drugs have gained much attention. METHODS Here, we review the potential of the most widely used fluoroquinolones, ciprofloxacin, levofloxacin and moxifloxacin for

The neuronal 5-HT3 receptor network after 20 years of research--evolving concepts in management of pain and inflammation.

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The 5-HT3 receptor is a pentameric ligand-gated cation channel which is found in the central and peripheral nervous system and on extraneuronal locations like lymphocytes, monocytes and fetal tissue. Five monomer subtypes, the 5-HT(3A-E) subunits, have been identified which show differences in the

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