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thalictrum tuberosum/antineoplàstic

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Background: Plants are an important origin of natural substances that the raw material for various pharmaceutical and therapeutic applications due to the presence of phytochemicals, such as alkaloids. Alkaloids, which are found in different plant species, possess numerous biological

Antitumor aporphine alkaloids from Thalictrum wangii.

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Nine new isoquinoline alkaloids, including two proaporphine (1-2), three aporphine (3-5), two oxoaporphine (6-7), and two seco-bisbenzylisoquinoline (8-9), together with three known alkaloids (10-12) were isolated from the whole plant of Thalictrum wangii. Their structures were established on the

[Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum].

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The total alkaloids of T. glandulosissimum and its main component hernandezine were found to be effective for treatment of mice bearing P388 leukemia, S180 ascites and C26 colon cancer. Although hernandezine inhibited the growth of mouse L1210 cells and human oral cancer KB cells in vitro markedly,

A triterpenoid from Thalictrum fortunei induces apoptosis in BEL-7402 cells through the P53-induced apoptosis pathway.

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Thalictrum fortunei S. Moore, a perennial plant distributed in the southeastern part of China, has been used in Traditional Chinese Medicine for thousands of years for its antitumor, antibacterial and immunoregulatory effects. In order to investigate the active components and the mechanism of the
Benzylisoquinoline alkaloids (BIAs) are produced in a wide variety of plants and include many common analgesic, antitussive, and anticancer compounds. Several members of a distinct family of S-adenosylmethionine (SAM)-dependent N-methyltransferases (NMTs) play critical roles in BIA biosynthesis, but
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