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Pàgina 1 des de 377 resultats
[Vomiting associated with weight stagnation and convulsions: urea cycle disorder should be suspected].
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In some inherited metabolic diseases, in particular in urea cycle disorders, which are usually diagnosed in neonatal period or in childhood, vomiting is often the first symptom. We report a case of late revelation of urea cycle disorder in a 13 years old female patient hospitalized for convulsions
Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats.
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The present study aimed to investigate the anticonvulsant activity as well as the effects on the level of hippocampal amino acid neurotransmitters (glutamate, aspartate, glycine and GABA) of N-(2-propylpentanoyl)urea (VPU) in comparison to its parent compound, valproic acid (VPA). VPU was more
Fatal coma in a young adult due to late-onset urea cycle deficiency presenting with a prolonged seizure: a case report.
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BACKGROUND
Unexplained hyperammonemic coma in adults can be a medical dilemma in the absence of triggering factors and known comorbidities. Ornithine transcarbamylase deficiency presents most commonly with hyperammonemic coma. Although a rare disorder, ornithine transcarbamylase deficiency is the
Urea cycle disorder presenting as bilateral mesial temporal sclerosis - an unusual cause of seizures: a case report and review of the literature.
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BACKGROUND
Urea cycle disorders are secondary to defects in the system converting ammonia into urea, causing accumulation of ammonia and other byproducts which are neurotoxic. Ornithine transcarbamylase deficiency is the most common of the urea cycle disorders and frequently presents with coma or
Urea-induced myoclonic seizures. An experimental study of site of action and mechanism.
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Experimental urea-induced myoclonic seizures: mechanism and site of action.
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Convulsion in urea-ammonia poisoning in goats and rabbits.
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Effect of convulsions induced by pentylenetetrazole or electricity on the dispositions of creatinine and urea in rats.
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THE EFFECT OF HYPERTONIC UREA SOLUTION ON ELECTROSHOCK SEIZURE THRESHOLD AND ELECTROLYTE DISTRIBUTION IN RATS.
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Use of mesoxalyl urea (alloxan) in treatment of an infant with convulsions due to idiopathic hypoglycemia.
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Fatal hyperammonemia after renal transplant due to late-onset urea cycle deficiency: a case report.
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We present a case of severe hyperammonemia with subsequent brain herniation in an adult man after renal transplantation. After successful surgery and an initially uneventful postoperative course, the patient developed significant mental status changes associated with seizure activity. His condition
Genetic approaches to studying mouse models of human seizure disorders.
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In conclusion, we have discussed a reverse genetics approach to studying seizure disorders in mice (Fig. 1), employing a targeted mutagenesis method to exploit the genetic defects identified in human epilepsy families. After detailed characterization of the nature of the human mutation and the mouse
Assessing the prevalence distribution of abnormal laboratory tests in patients with simple febrile seizure.
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BACKGROUND
Febrile seizure is an important issue in pediatric practice. Even some pediatricians do not have a proper approach to febrile seizure, making the sick child undergo complex laboratory tests or invasive procedures or even long-term treatment with anticonvulsant drugs. In spite of multiple
Seizure disorder in the men of a Veterans Administration nursing home.
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This study examined the descriptive epidemiology of seizure disorder in 129 male residents of a Veterans Administration Nursing Home. Eighty-seven of the residents were institutionalized because of nonpsychiatric disorders (60 for chronic neurologic diseases, and 27 for other medical conditions).
The anti-epileptogenic and cognition enhancing effect of novel 1-[4-(4-benzo [1, 3] dioxol-5-ylmethyl-piperazin-1-yl)-phenyl]-3-phenyl-urea (BPPU) in pentylenetetrazole induced chronic rat model of epilepsy.
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Epilepsy is a chronic neurological disorder which affects 65 million worldwide population and characterized by recurrent seizure in epileptic patients. Recently, we reported a novel piperonylpiperazine derivative, BPPU "1-[4-(4-benzo [1,3]dioxol-5-ylmethyl-piperazin-1-yl)- phenyl]-3-phenyl-urea'' as
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