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visceral pain/nàusea

L'enllaç es desa al porta-retalls
5 resultats

Sulphonamide derivatives, their preparation and their therapeutic application

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FIELD OF THE INVENTION The present invention relates to sulfonamide derivatives, to the process for preparing them and to their therapeutic use. BACKGROUND OF THE INVENTION Orexins A and B (or hypocretins 1 and 2) are hypothalamus neuropeptides of 33 and 28 amino acids, respectively, recently

Chromane substituted benzimidazole derivatives

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BACKGROUND OF THE INVENTION This invention relates to chromane substituted benzimidazole derivatives. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for

Chromane substituted benzimidazole derivatives as acid pump antagonists

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BACKGROUND OF THE INVENTION This invention relates to chromane substituted benzimidazole derivatives. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for

Benzimidazole derivatives as selective acid pump inhibitors

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BACKGROUND OF THE INVENTION This invention relates to tricyclic compounds. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of disease

Use of orexin receptor antagonists

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The present invention relates to the use of orexin receptor antagonists as neuroprotectants, and in the treatment of nausea and vomiting, irritable bowel syndrome and other conditions associated with visceral pain. Many medically significant biological processes are mediated by proteins
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