visceral pain/obesitat

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Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity.

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Exposure to high-fat diet induces both, peripheral and central alterations in TLR4 expression. Moreover, functional TLR4 is required for the development of high-fat diet-induced obesity. Recently, central alterations in TLR4 expression have been associated with the modulation of visceral pain.

Chronic abdominal wall pain: prevalence in out-patients.

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BACKGROUND Chronic abdominal wall pain (CAWP) is a frequent and confusing pain. It often leads to many diagnostic tests and sometimes some surgeries before an accurate diagnosis is achieved. Numerus had reported that patients with pain in abdominal wall are frequently treated like some one who is

An atypical case of nephrolithiasis with transient remission of symptoms following spinal manipulation.

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OBJECTIVE Nephrolithiasis is a common condition with symptoms similar to common mechanical lesions of the lumbar spine and pelvis. The purpose of this report is to outline a case of nephrolithiasis that closely mimicked sacroiliac joint syndrome in subjective report, objective findings, and

Severity of interstitial cystitis symptoms and quality of life in female patients.

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OBJECTIVE Interstitial cystitis (IC) is a visceral pain syndrome with a profound impact on quality of life (QOL). The main aims of the current study are as follows: (1) to determine possible factors that may increase the severity of symptoms and decrease QOL in women diagnosed with IC; (2) to study

Maternal high-fat diet prevents developmental programming by early-life stress.

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Anxiety disorders and depression are well-documented in subjects exposed to adverse childhood events. Recently, maternal obesity and/or maternal consumption of high-fat diets (HFD) have been also proposed as risk factors for offspring mental health. Here using an animal model in rats, we explored

Risk factors and early pharmacological interventions to prevent chronic postsurgical pain following cardiac surgery.

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Chronic postsurgical pain (CPSP) after cardiac surgery represents a significant clinical problem. The prevalence of CPSP varies widely between studies, but severe CPSP is present in less than 10% of the patients. Important differential diagnoses for CPSP after cardiac surgery are myocardial

The microbiome of the oral mucosa in irritable bowel syndrome.

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Irritable bowel syndrome (IBS) is a poorly understood disorder characterized by persistent symptoms, including visceral pain. Studies have demonstrated oral microbiome differences in inflammatory bowel diseases suggesting the potential of the oral microbiome in the study of non-oral conditions. In

The therapeutic potential of purinergic signalling.

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This review is focused on the pathophysiology and therapeutic potential of purinergic signalling. A wide range of diseases are considered, including those of the central nervous system, skin, kidney, musculoskeletal, liver gut, lower urinary tract, cardiovascular, airways and reproductive systems,

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