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alpha mannosidase/zubní kaz

Odkaz je uložen do schránky
ČlánkyKlinické testyPatenty
13 Výsledek

Virtual screening and QSAR study of some pyrrolidine derivatives as α-mannosidase inhibitors for binding feature analysis.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Virtual screening and QSAR analysis were carried out to investigate the binding features of (2R, 3R, 4S)-2-aminomethylpyrrolidine 3,4-diol and the functionalized pyrrolidine derivatives to the α-mannosidase I and II enzymes. The QSAR models (possessed considerable R(2), Q(2) values, etc.) suggested
Fungi are elements of the ontocenosis of the oral cavity and causal factors of inflammatory lesions in its mucous membrane. The objective of the study was to find differences in the activity of hydrolytic enzymes of Candida albicans isolated from patients with diseases of the periodontium and mucous

Cloning, Expression, and Characterization of Capra hircus Golgi α-Mannosidase II.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Golgi α-mannosidase II (GMII), a key glycosyl hydrolase in the N-linked glycosylation pathway, has been demonstrated to be closely associated with the genesis and development of cancer. In this study, we cloned cDNA-encoding Capra hircus GMII (chGMII) and expressed it in Pichia pastoris expression

Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Golgi alpha-mannosidase II, a key enzyme in N-glycan processing, is a target in the development of anti- cancer therapies. The crystal structure of Drosophila Golgi alpha-mannosidase II in the absence and presence of the anti-cancer agent swainsonine and the inhibitor deoxymannojirimycin reveals a

Diagnostic potential of lysosomal hydrolases in body cavity effusions.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Hexosaminidase, alpha-mannosidase, beta-galactosidase, beta-glucuronidase, and arylsulphatase A were measured inperitoneal and pleural effusions from patients with benign, malignant, and inflammatory disorders. Compared with the benign transudates, all enzyme activities were moderately elevated in

Lysosomal exoglycosidases in nasal polyps.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND Nasal polyps are smooth outgrowths assuming a shape of grapes, formed from the nasal mucosa, limiting air flow by projecting into a lumen of a nasal cavity. Up to now the surgical resection is the best method of their treatment, but etiology and pathogenesis of the nasal polyps is not yet

Activity of lysosomal exoglycosidases in saliva of patients with HIV infection.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE The aim of this work was to evaluate the influence of HIV infection on the catabolism of glycoconjugates in the oral cavity, by determination of the activity of lysosomal exoglycosidases in mixed saliva. METHODS The specific activities of the following exoglycosidases were tested:

Increased activity of lysosomal enzymes in the peritoneal fluid of bacterial peritonitis.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE The activity of lysosomal enzymes is increased in the cerebrospinal fluid of bacterial meningitis, suggesting that inflammation may cause leakage of lysosomal enzymes into the extracellular fluid. Our objective was to study the activity of 3 lysosomal enzymes in cell-free peritoneal fluid

Enhanced enzymatic activity of Candida species responsible for oral candidiasis in renal transplant recipients.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Renal transplant recipients (RTRs) are regarded to be predisposed to oral candidiasis. This study was undertaken to evaluate the activity of hydrolytic enzymes in strains causing oral candidiasis in RTR. A total of 123 Candida albicans and 10 Candida krusei strains were isolated from 200 RTRs (39

Growth of toxic-shock-syndrome strain of Staphylococcus aureus after enzymic degradation of 'Rely' tampon component.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
beta-glucosidase, cellulase, alpha-mannosidase, beta-galactosidase, and N-acetyl-beta-glucosaminidase were tested for their ability to hydrolyse the carboxymethylcellulose contained in 'Rely' tampons (R-CMC). The end-products of the hydrolysis were determined by chromatography. Only beta-glucosidase

Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Endoplasmic reticulum (ER) class I alpha1,2-mannosidase (also known as ER alpha-mannosidase I) is a critical enzyme in the maturation of N-linked oligosaccharides and ER-associated degradation. Trimming of a single mannose residue acts as a signal to target misfolded glycoproteins for degradation by
One method of treatment used in cancer therapy is radiotherapy which can injure the oral, pharynx or larynx mucosa and predisposes tissue to the development of fungal infections. The aim of the study paper was the mycological examinations of swabs from the oral cavity and pharynx of patients

Inhibition of human seminal fluid and Leishmania donovani phosphatases by molybdate heteropolyanions.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Inhibition of a tartrate-resistant acid phosphatase (ACP) from Leishmania donovani and the tartrate-sensitive ACP from human seminal fluid (prostatic ACP) was examined using a series of 13 molybdate-containing heteropolyanions. The heteropolyanions were divided into four groups based on the number
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