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Strana 1 z 37 Výsledek
Alkyl, alkenyl and alkynyl chrysamine G derivatives for inhibition of cell degeneration and toxicity associated with amyloid deposition
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The present invention was made utilizing funds from the National Institute of Ageing, grant numbers AG-05443, AG-05133 and AG-08974. This application is a continuation-in-part of U.S. patent application Ser. No. 08/640,704, now abandoned, and also a continuation-in-part of International Patent
Apparatus and method for detecting amyloid in a retina in a diagnosis, advancement, and prognosing of alzheimer's disease, traumatic brain injury, macular degeneration and a plurality of neurodegenerative dissorders, and ocular diseases
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
TECHNICAL FIELD & BACKGROUND
Imaging of amyloid-beta plaques (including amyloid, amyloid-beta peptides) and other pathology and anatomical features in the retina or brain is often unobtainable without the use of specialized contrast agents, or autofluorescence techniques. While drusen and
Apparatus to detect amyloid in a patient user's retina in a diagnosis, advancement and prognosis of alzheimer's disease, traumatic brain injury, macular degeneration and a plurality of neurodegenerative disorders and ocular diseases
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
TECHNICAL FIELD & BACKGROUND
Imaging of amyloid-beta plaques including amyloid, amyloid-beta peptides and other pathology and anatomical features in a patient user's retina or a patient user's brain is often unobtainable without the utilization of specialized contrast agents or autofluorescence
Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention relates to the identification of compounds that are suitable for imaging amyloid deposits in living patients. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of
Compound for the antemortem diagnosis of Alzheimer's Disease and in vivo imaging and prevention of amyloid deposition
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention relates to the identification of compounds that are suitable for imaging amyloid deposits in living patients. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of
Humanized anti-beta-amyloid antibodies
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
FIELD OF THE INVENTION
The present invention relates to antigen binding proteins, including antibodies, that bind .beta.-amyloid peptide and in particular human .beta.-amyloid peptide. The present invention also concerns methods of treating diseases or disorders characterised by elevated
Methods for treatment of beta-amyloid protein-induced ocular disease
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to the use of natural product compounds isolated from plants, and synthetic chemical analogues thereof, for the prevention and treatment of beta-Amyloid protein-induced disease. Specifically, the invention relates to
Antigen binding proteins
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
This application is a 371 of International Application No. PCT/EP2008/062652, filed Sep. 23, 2008, which claims the priority of GB Application No. 0718737.0, filed Sep. 25, 2007, which are incorporated herein in their entirety.
FIELD OF THE INVENTION
The present invention relates to methods of
Compounds for inhibiting protein aggregation, and methods for making and using them
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
TECHNICAL FIELD
This invention generally relates to protein chemistry, cell biology, neuroscience and medicine. The invention provides compositions comprising protein aggregation inhibitors, and pharmaceutical compositions comprising them, and methods for making and using them, including methods for
Compounds for reversing and inhibiting protein aggregation, and methods for making and using them
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
TECHNICAL FIELD
This invention generally relates to protein chemistry, cell biology, neuroscience and medicine. The invention provides compositions for increasing the clearance of protein aggregates such as amyloid beta protein (A.beta.) aggregates, and pharmaceutical compositions comprising them,
Mono-fluoro beta-secretase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
FIELD OF THE INVENTION
The present invention relates to novel compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to
Compounds and their use as BACE inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The present invention relates to compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to compounds, which are
Compounds and their use as BACE inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The present invention relates to compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to compounds, which are
Substituted isoindoles for the treatment and/or prevention of A.beta.- related pathologies
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
TECHNICAL FIELD OF THE INVENTION
The present invention relates to novel compounds and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of A.beta.-related pathologies such as Downs syndrome, .beta.-amyloid
Compounds and their use as BACE inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The present invention relates to compounds and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as medicaments for treatment and/or prevention of various diseases. In particular the invention relates to compounds, which are
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Zadejte symptom nebo chorobu a přečtěte si o bylinách, které by vám mohly pomoci, napište bylinu a podívejte se na nemoci a příznaky, proti kterým se používá.
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