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anticoagulant/karcinom prsu

Odkaz je uložen do schránky
Strana 1 z 174 Výsledek

Inhibition of adhesion breast cancer cells by anticoagulant drugs and cimetidine.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Recent studies suggest that anticoagulant drugs and cimetidine therapy in malignancy may improve cancer survival and inhibit the metastatic process. In this study we investigated and compared the effects of anticoagulant drugs (unfractionated heparin, warfarin, acetylsalicylic acid,

Anticoagulant medication at time of needle biopsy for breast cancer in relation to risk of lymph node metastasis.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Anticoagulant treatment might enhance the natural defense against tumor cell dissemination caused by diagnostic needle biopsy by counteracting thrombocyte coating of such cells. To clarify whether women using anticoagulant treatment at the time of biopsy have a lower occurrence of lymph node

In Vitro Comparison of the Role of P-Glycoprotein and Breast Cancer Resistance Protein on Direct Oral Anticoagulants Disposition.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND Pharmacokinetics of direct oral anticoagulants (DOACs) are influenced by ATP-binding cassette (ABC) transporters such as P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). OBJECTIVE To better understand the role of transporters in DOAC disposition, we evaluated and

Anticoagulants and breast cancer survival, a nationwide cohort study.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Various components of the coagulation cascade have been linked to breast cancer (BrCa) progression. In vivo results suggest that anticoagulants possess anticancer properties, but there are virtually no studies in human populations. Our nationwide study explored the association between
Background: Atrial fibrillation (AF) is a frequent comorbidity in malignant patients. Anticancer therapies complicate anticoagulant strategy. We evaluated the safety and efficacy of long-term use of direct oral anticoagulants (DOACs) in

The direct oral anticoagulants rivaroxaban and dabigatran do not inhibit orthotopic growth and metastasis of human breast cancer in mice.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Essentials Factor Xa (FXa)-targeting direct oral anticoagulants (DOACs) reduce venous thromboembolism (VTE) The effects of FXa-targeting DOACs on cancer progression remain to be studied In xenograft models, a FXa-targeting DOAC did not inhibit breast cancer growth and metastasis A thrombin-targeting

λ-Carrageenan Oligosaccharides of Distinct Anti-Heparanase and Anticoagulant Activities Inhibit MDA-MB-231 Breast Cancer Cell Migration.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
In tumor development, the degradation of heparan sulfate (HS) by heparanase (HPSE) is associated with cell-surface and extracellular matrix remodeling as well as the release of HS-bound signaling molecules, allowing cancer cell migration, invasion and angiogenesis. Because of their structural

Oral anticoagulants in the postoperative treatment of breast cancer: two years' experience.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace

Increased tumor uptake of chemotherapeutics and improved chemoresponse by novel non-anticoagulant low molecular weight heparin.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND Recent prospective clinical trials of low molecular weight heparins (LMWHs) have demonstrated that these agents may provide significant advantages in terms of progression-free and overall survival in certain subgroups of cancer patients. The mechanisms of improved survival associated with

The effect of very-low-dose warfarin on markers of hypercoagulation in metastatic breast cancer: results from a randomized trial.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Malignancy is a risk factor for thromboembolism and anti-cancer chemotherapy can increase this risk. Prophylaxis of thrombosis with very-low-dose warfarin given concurrently with chemotherapy has a significantly reduced rate of thromboembolism in a randomized trial in women with stage IV breast

[A Case Report of Luminal A Male Inflammatory Breast Cancer that Was Difficult to Treat Because of Trousseau Syndrome].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
This report describes the case of a 67-year-old male with inflammatory breast cancer. He had noticed a left breast mass about seven years previously, but he had ignored it. He then visited our hospital 4 months previously when multiple small masses occurred in the left front chest wall. The tumor

The association of protease activated receptor 1 gene -506 I/D polymorphism with disease-free survival in breast cancer patients.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND Recent data have shown that tumor development and dissemination may be regulated by procoagulant/anticoagulant axis. The aim of the present study was to search for an association of the protease activated receptor (PAR)1 gene -506 insertion/deletion (I/D), factor V Leiden (FVL),

Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Activated protein C (APC), an anticoagulant serine protease, has been shown to have non-hemostatic functions related to inflammation, cell survival, and cell migration. In this study we investigate the mechanism by which APC promotes angiogenesis and breast cancer invasion using ex vivo and in vitro

Fulvestrant: pharmacologic profile versus existing endocrine agents for the treatment of breast cancer.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE To compare the pharmacologic profile of fulvestrant with that of tamoxifen and the aromatase inhibitors with respect to the choice of treatment for advanced breast cancer (ABC). METHODS Principal literature and review articles were obtained from MEDLINE (1991-March 2006). Key search terms

Impact of anticoagulant choice on hospitalized bleeding risk when treating cancer-associated venous thromboembolism.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Essentials Bleeding risk by anticoagulant choice for cancer-associated venous thrombosis (CA-VTE) is unknown. 26 894 people with CA-VTE were followed for bleeding in a claims database in the United States. Hospitalized bleeding risk was similar with direct acting oral anticoagulants vs. warfarin.
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