The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections; ##STR00001##

Bioderm Research

Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals

The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars, and isomers and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections; ##STR00001##

Artemisinin derivatives with natural amino acids, peptides, and amino sugars for the treatment of infection and topical condition in mammals

The present invention teaches a new and innovative pharmaceutical composition and method for the treatment of age-related macular degeneration in a patient in need thereof. In particular, the present invention teaches the administration of artemisone for the treatment and/or prevention of AMD in a patient in need thereof. This invention relates to one certain extract of the Artemisia annua plant, both in its crude and refined form composed substantially of Artemisone, a compound that is chemically classified as a sesquiterpene with an endo-peroxide group [FIG. 1]. The present invention teaches a for the treatment of either wet or dry age-related macular degeneration. The invention provides for an initial treatment using an intravitreal injection of Artemisone followed by the use of an oral dosage form which is designed to maintain the therapeutic concentration of Artemisone in the eye without having to perform constant intravitreal injections into the eye.

Parsonson; Peter Shepherd

Pharmaceutical composition and method for treating age-related macular degeneration

A method of making a preparation having effect against allergic symptoms, more particularly a preparation which has proved to be effective for therapeutic and prophylactic relief or prevention of symptoms associated eith allergic rhinitis, asthmatic conditions and other allergic conditions, such as allergic conjunctivitis, urticaria, or insect or plant stings, and in which fresh, newly harvested plants of the species Artemisia or other davanon containing plants are boiled in water (1), whereby water steam and volatile essential oils are given off, said oils are collected (2), the residue green mass is heated in water to allow for hydrolysis of the chemical components (3) which are extracted with alcohol (4) and are mixed with the previously extracted essential oils. The alcohol extract could be exchanged for an extract of another plant (e.g. thyme or chamomile) containing spasmolytic or antiallergic components. The invention also relates to a preparation made according to the method.

artemisia/antimykotikum

Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals

Artemisinin derivatives with natural amino acids, peptides, and amino sugars for the treatment of infection and topical condition in mammals

Pharmaceutical composition and method for treating age-related macular degeneration

Artemisia extract for treating allergies

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