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carboxylic acid/nauzea

Odkaz je uložen do schránky
ČlánkyKlinické testyPatenty
Strana 1 z 18 Výsledek

Omega-3-carboxylic acid (Epanova) for hypertriglyceridemia.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Hypertriglyceridemia is a prevalent yet under-addressed condition, often seen in association with uncontrolled diabetes mellitus, obesity, and physical inactivity. The control of triglyceride (TG) levels is essential to prevent the development of coronary artery disease and pancreatitis associated

Delta9-tetrahydrocannabivarin as a marker for the ingestion of marijuana versus Marinol: results of a clinical study.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Delta9-tetrahydrocannabinol (THC), the main psychologically active ingredient of the cannabis plant (marijuana), has been prepared synthetically and used as the bulk active ingredient of Marinol, which was approved by the FDA for the control of nausea and vomiting in cancer patients receiving

Adrenal insufficiency in a woman secondary to standard-dose inhaled fluticasone propionate therapy.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
A 55-year-old woman with asthma presented with adrenal insufficiency of unknown origin. She was referred to our Division of Reproductive Endocrinology to further evaluate an undetectable morning cortisol level discovered during the evaluation of a low serum DHEA-S level. She was asymptomatic other
For the purpose of evaluation of clinical efficacy, safety and usefulness on Salmonella enteritis, T-3262 (Tosufloxacin tosilate), a newly developed pyridone-carboxylic acid derivative, was administered to a total of 103 patients and carriers. In addition, in vitro antibacterial activity of T-3262

Norfloxacin: review of safety studies.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The tolerability profile of norfloxacin, the first of a new generation of fluoroquinolone carboxylic acid antibacterials, has been defined in numerous laboratory animal and human trials. Whether administered for moderate or protracted periods, norfloxacin has been relatively safe in animals over a

Symptoms and immunologic markers among vulcanization workers in rubber industries in southern Sweden.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE The aim of this study was to estimate the risk of symptoms and the possible derangement of levels of immunologic markers for contemporary Swedish rubber workers. Furthermore, the relation between exposure and these biomarkers of response was examined using urinary levels of

Occupational hygiene in a Finnish drum composting plant.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Bioaerosols (microbes, dust and endotoxins) and volatile organic compounds (VOCs) were determined in the working air of a drum composting plant treating source-separated catering waste. Different composting activities at the Oulu drum composting plant take place in their own units separated by

The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The absorption, metabolism, and excretion of [14C]aprepitant, a potent and selective human substance P receptor antagonist for the treatment of chemotherapy-induced nausea and vomiting, was evaluated in rats and dogs. Aprepitant was metabolized extensively and no parent drug was detected in the

Therapeutic efficacy and safety of pidotimod in the treatment of urinary tract infections in children.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The activity of pidotimod ((R)-3-[(S)-(5-oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, PGT/1A, CAS 121808-62-6) was studied vs. placebo in a double-blind, randomized, multicentre trial, involving 60 pediatric patients with recurrent urinary tract infections. Recovery from acute

Phase II study of lonidamine in patients with small cell carcinoma of the lung.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Lonidamine, a substituted indazole carboxylic acid that inhibits cellular respiration, was given in an escalating oral schedule to 20 evaluable patients with measurable extensive small cell carcinoma of the lung. Two partial responses occurred. Reversible acceptable toxicity included myalgia,

[Basic and clinical studies on norfloxacin in the pediatric field].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Pharmacokinetic , bacteriological and clinical studies on norfloxacin (NFLX), a quinolone-carboxylic acid antibacterial agent, were conducted in the pediatric field. 1. Serum concentrations and urinary excretion of NFLX after single dose of 2.2 approximately 5.6 mg/kg (mean 4.4 +/- 1.2 mg/kg) were

[Clinical study on fleroxacin in surgical infections].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
We conducted clinical studies on fleroxacin (FLRX), a new pyridone carboxylic acid derivative, for the treatment of periproctal abscess, secondary infections (due to wounds, burns or surgical operations), mastitis or areolitis and others with once daily dose of 200 mg or 300 mg. We obtained the

Phase II evaluation of Lonidamine in patients with advanced malignancy.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Lonidamine, a substituted indazole carboxylic acid with unique effects on cellular respiration, was studied in 27 patients with advanced malignancies. Of the 18 evaluable patients, 5 had small-cell lung cancer, 3 had non-small-cell lung cancer, 3 sarcoma, 2 breast cancer, and 5 other tumour types.

Phase I trial of temozolomide (NSC 362856) in patients with advanced cancer.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Temozolomide (TMZ) is a new imidazotetrazine derivative with early clinical activity in glioma and melanoma. The purpose of this Phase I study is to characterize the toxicity, pharmacokinetics, and antitumor activity of TMZ administered on an oral 5-day schedule to patients with or without prior

Phase I and pharmacokinetic study of brequinar (DUP 785; NSC 368390) in cancer patients.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Brequinar (DUP 785, NSC 368390) is a 4-quinoline carboxylic acid derivative with broad spectrum antitumour activity in experimental models that acts as an antimetabolite by specific inhibition of de novo pyrimidine synthesis. We performed a phase I study of brequinar administered as a 10 min
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