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dibutyl phthalate/kukuřice setá
Odkaz je uložen do schránky
12 Výsledek
[Glucocorticoid pathway mediated the inhibition of testosterone in rats exposed to dibutyl phthalate].
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE
To investigate the inhibitory mechanisms of testosterone (T) biosynthesis in rats exposed to dibutyl phthalate (DBP).
METHODS
Male Wistar rats were randomly divided into five groups by weight, including 0.25, 0.50, 1.00, 2.00 g/kg DBP groups and corn oil control group, with 16 rats in each
Neurotoxicity of dibutyl phthalate in brain development following perinatal exposure: a study in rats.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Dibutyl-phthalate (DBP) is a ubiquitous environmental contaminant. However, its neurotoxic effects on neonatal, immature or mature brains remain unclear. Here, we aimed to investigate the neurotoxicity of perinatal exposure of DBP on rodent offspring animals. Pregnant rats received intragastric DBP
[Effects of prepubertal continuous exposure to dibutyl phthalate on testicular development in rats].
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE
To investigate the effects of prepubertal continuous exposure to dibutyl phthalate (DBP) on the testis development in SD rats.
METHODS
Twenty-one-day-old weanling prepubertal male SD rats were randomly divided into a control (n = 24) and an experiment group (n = 54), gavaged daily with
Dibutyl phthalate-induced neurotoxicity in the brain of immature and mature rat offspring.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE
We aim to investigate the neurotoxicity induced by perinatal exposure of dibutyl phthalate (DBP) on the immature and mature offspring animals using a rodent model.
METHODS
Pregnant rats were given intragastric administration of 500mg/kg body weight DBP daily from gestational day 6 to
Data on the activity of DNA methyltransferase in the uteri of CD-1 mice exposed to dibutyl phthalate.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Phthalates are industrial chemicals used as plasticizers in food packaging, medical devices, and toys, as well as cosmetics used primarily by women. Epidemiological studies in women and animal studies using rodents have reported associations between phthalate exposures and adverse reproductive
Environmentally Relevant Exposure to Dibutyl Phthalate Disrupts DNA Damage Repair Gene Expression in the Mouse Ovary.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Phthalates have a history of reproductive toxicity in animal models and associations with adverse reproductive outcomes in women. Human exposure to dibutyl phthalate (DBP) occurs via consumer products (7-10 μg/kg/day) and medications (1-233 μg/kg/day). Most DBP toxicity studies have focused on high
Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Male reproductive tract abnormalities associated with testicular dysgenesis in humans also occur in male rats exposed gestationally to some phthalate esters. We examined global gene expression in the fetal testis of the rat following in utero exposure to a panel of phthalate esters. Pregnant
Intrauterine exposure to low-dose DBP in the mice induces obesity in offspring via suppression of UCP1 mediated ER stress
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Dibutyl phthalate (DBP) is recognized as an environmental endocrine disruptor that has been detected in fetal and postnatal samples. Recent evidence found that in utero DBP exposure was associated with an increase of adipose tissue weight and serum lipids in offspring, but the precise mechanism is
Exposure to an environmentally relevant phthalate mixture during prostate development induces microRNA upregulation and transcriptome modulation in rats.
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Přihlášení Registrace
Environmental exposure to phthalates during intrauterine development might increase susceptibility to neoplasms in reproductive organs such as the prostate. Although studies have suggested an increase in prostatic lesions in adult animals submitted to perinatal exposure to phthalates, the molecular
Toxic Effects of the Mixture of Phthalates and Bisphenol A-Subacute Oral Toxicity Study in Wistar Rats.
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Přihlášení Registrace
Phthalates and bisphenol A, classified as endocrine disruptors, have weak estrogenic, anti-androgenic properties, and affect thyroid hormone regulation. The aim of this study on male rats was to compare the subacute toxic effects of low doses of single compounds (bis (2 -ethylhexyl) phthalate
Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Phthalates are used in a large variety of products, such as building materials, medical devices, and personal care products. Most previous studies on the toxicity of phthalates have focused on single phthalates, but it is also important to study the effects of phthalate mixtures because humans are
Exposure to an Environmentally Relevant Phthalate Mixture Causes Transgenerational Effects on Female Reproduction in Mice.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Phthalates are used in consumer products and are known endocrine-disrupting chemicals. However, limited information is available on the effects of phthalate mixtures on female reproduction. Previously, we developed a phthalate mixture made of 35% diethyl phthalate, 21% di(2-ethylhexyl) phthalate,
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