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disulfide/cévní mozková příhoda

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It is known that the neutrophil/lymphocyte ratio (NLR) is associated with adverse outcomes in ischemic stroke patients. We aimed to reveal the association of NLR and thiol/disulfide homeostasis (TDH) with ischemic stroke patients.This study was conducted

Dynamic thiol-disulfide homeostasis in acute ischemic stroke patients.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Dynamic thiol-disulfide homeostasis plays a critical role in the cellular protection provided by antioxidation. The aim of this study was to investigate whether there is a change in thiol-disulfide homeostasis in acute ischemic stroke patients. Patients diagnosed with acute ischemic stroke that had

Eight at one stroke - a synthetic tetra-disulfide peptide epitope.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
We have designed a cysteine-rich β-hairpin peptide which dimerises spontaneously to the antiparallel double β-hairpin motif C1-C12', C1'-C12, C5-C8, C5'-C8'-tricyclo-(CHWECCitGCRLVC)2. The highly regioselective oxidation of eight cysteines yields an intermolecular bi-disulfide 24mer hinge peptide

Disturbance of thiol/disulfide aminothiols homeostasis in patients with acute ischemic stroke stroke: Preliminary findings.

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Přihlášení Registrace
To determine the disruption of low-molecular-weight aminothiols (LMWTs: cysteine, cysteinylglycine, homocysteine, and glutathione) homeostasis in blood plasma during the acute and early subacute stages after ischemic stroke.We admitted 41 patients with

[Blood cell aggregation and oxidative stress in pathogenesis of ischemic stroke].

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Přihlášení Registrace
Rheologic properties of blood cells and a state of oxidative-reductive processes and blood systems have been studied in 75 patients in acute period of ischemic stroke. The signs of oxidative stress development and simultaneous augmentation of blood cells aggregation were found. Shifts of

Severe hypotension and ischemic stroke after disulfiram-ethanol reaction.

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Přihlášení Registrace
Disulfiram (tetraethylthiuram disulfide) has been used for almost 60 years in the treatment of alcohol addiction. It causes aversive behavior due to disulfiram-ethanol reaction (DER). The classical DER includes flush, sweating, tremor, nausea, vomiting, tachycardia, moderate decrease in blood

Mortality among workers exposed to carbon disulfide.

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Přihlášení Registrace
Mortality experience was investigated at a plant in Ontario that produced viscose rayon, with carbon disulfide as a main raw material. Work-history records for 279 deceased workers at the plant (plant A) were obtained and compared with those for 511 deceased workers at a pulp and paper plant in the

Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke.

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Přihlášení Registrace
BACKGROUND Lipid lowering agent such as agonists of peroxisome proliferator-activated receptors (PPAR) are suggested as neuroprotective agents and may protect from the sequelae of brain ischemic stroke. Although the demonstration is not clearly established in human, the underlying molecular

Targeting the Role of Lipoprotein (a) in Stroke.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Stroke is the third leading cause of death in the United States, behind only heart disease and cancer, with over 140,000 associated deaths per year. Considerable research is ongoing to examine the role of modifiable risk factors which may cause or contribute to stroke. Although age and family

Thiol-Disulfide Homeostasis in Cerebral Venous Sinus Thrombosis.

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Přihlášení Registrace
The objective of this study is to examine thiol-disulfide homeostasis in patients with cerebral venous sinus thrombosis.Fifty-three patients diagnosed with cerebral venous sinus thrombosis and 80 healthy volunteers were included in the study. The native

Distinct structural changes in wild-type and amyloidogenic chicken cystatin caused by disruption of C95-C115 disulfide bond.

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Přihlášení Registrace
Human cystatin C (HCC) amyloid angiopathy (HCCAA) is characterized by tissue deposition of amyloid fibrils in blood vessels, which can lead to recurrent hemorrhagic stroke. Wild-type HCC forms part of the amyloid deposits in brain arteries of elderly people with amyloid angiopathy. A point mutation

Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke.

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Přihlášení Registrace
Homocyst(e)ine refers to the sulfur-containing amino acids homocysteine, homocystine, and homocysteine-cysteine mixed disulfide, which normally exist in plasma in both the free and protein-bound forms. Marked hyperhomocyst(e)inemia is associated with well-recognized complications of occlusive

Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Induction of protein disulfide isomerase (PDI) is validated as a main mechanism by which 4-hydroxybenzyl alcohol (4-HBA), an active principle of Gastrodia elata Blume, reduces cerebral infarct volumes in a murine model of focal brain ischemia/reperfusion. In contrast to its position isomers, i.e.

Carbon disulfide neurotoxicity: Taiwan experience.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Carbon disulfide (CS2) intoxication may induce peripheral neuropathy, encephalopathy, and cardiovascular diseases. In our studies, abnormalities of the peripheral nerves including clinical symptoms and electrophysiological findings were still present 3 years after cessation of CS2 exposure. The data

Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
We isolated and identified a stress protein that is up-regulated in response to hypoxia in primary-cultured glial cells. Protein-disulfide isomerase (PDI) was up-regulated not only by hypoxia in glia in vitro, but also by transient forebrain ischemia in rats in vivo. To determine whether newly
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