Participants with ASA 1-2, aged 18-60 years, undergoing hypotensive anesthesia in the operation of the septoplasty in Recep Tayyip Erdoğan University Medical Faculty Training and Research Hospital. Participants with uncontrolled hypertension, diabetes mellitus, cerebrovascular disease, cogulopathy, morbid obesity (BMI ≥35) and renal disease will not be taken.
Participants were first pre-medicated with an infusion of midazolam 0.05 mg/kg, fentanyl 1 µg/kg, lidocaine 1 mg/kg. Induction of anesthesia was achieved with an infusion of propofol 1-2 mg/kg and vecuronium bromide 0.6 mg/kg and after 2 to 3 minutes participants were intubated with the appropriate tube size. Anesthesia was maintained with an infusion of remi fentanyl (0.05 - 1 µg/Kg/min), with oxygen (O2) in air with desflurane.

Nasal Septum Deviation

Recep Tayyip Erdogan University Training and Research Hospital

Effects of Hypotensive Anesthesia on Thiol Disulphide Balance

Oxidative stress marker, that shows dynamic thiol-disulphide homeostasis

Leyla Kazancıoğlu

Assistant Professor

Cystagon-EC

Sex: Female, Male

Region of Enrollment

Number of Improved Subjects

Normalization or >50% of Serum ALT Levels From Baseline

Overall Study

Dr. Joel Lavine

Fatty Liver

Drug is in enteric-coated capsule form. The dosage will begin at 1g/m-squared body surface area with a maximum dose of 1000mg twice daily. Treatment period is 3-6 months.

Cysteamine

University of California, San Diego School of Medicine General Clinic Research Center

A Preliminary Study to Evaluate Cysteamine Therapy in Human Subjects With Non-Alcoholic Steatohepatitis (NASH)

Joel Lavine

Professor

Raptor Pharmaceuticals Corp.

Subjects who are undergoing bariatric surgery

Subjects who qualify for bariatric surgery but do not undergo the procedure

Blood and exhaled breath condensate samples will obtained at all time points (baseline, 1 month, 6 months, and 1 year.

disulfide/obezita

Effects of Hypotensive Anesthesia on Thiol Disulphide Balance

A Preliminary Study to Evaluate Cysteamine Therapy in Human Subjects With Non-Alcoholic Steatohepatitis (NASH)

Study to Evaluate the Effects of Weight Loss on Airway Inflammation and Mechanics in Subjects With Asthma (Asthma-Bariatric Surgery Study)

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