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lipoxygenase/horečka
Odkaz je uložen do schránky
Strana 1 z 25 Výsledek
5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly, 3-hydroxybenzo[b]thiophene-2-carboxamides, which are found to be effective cyclooxygenase and 5-lipoxygenase inhibitors and are therefore useful in the treatment of inflammation and other prostaglandin and
N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to fused heterocyclic carboxamides, for example, N-(2,2-diphenylethenyl)-3-hydroxythieno[3,2-b]thiophene-2-carboxamide.
These novel compounds are found to be effective cyclooxygenase and 5-lipoxygenase inhibitors and are therefore useful in the
Lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is related to commonly assigned U.S. application Ser. Nos. 578,413, abandoned, for "Tumor Reducing Compositions," Allen, and 578,412, abandoned, "Antioxidant Compounds and Methods of Synthesis," Allen, et al., being filed in the U.S. Patent
N-alkenyl-2-hydroxybenzo(b)thiophene-3-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 2-hydroxybenzothiophenes having the unusual 3-enamido side chains, for example, ##STR1##
These novel compounds can be effective cyclooxygenase and 5-lipoxygenase inhibitors and therefore can be useful in the
N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 3-hydroxybenzothiophenes having the unusual 2-enamido side chains, for example, ##STR1##
These novel benzothiophenes are found to be effective cyclooxygenase and 5-lipoxygenase inhibitors and are therefore useful in
Derivatives of 3-hydroxyazabenzo(beta)thiophene useful as 5-lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
Derivatives of 3-hydroxyazabenzo[b]thiophene useful as 5-lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 3-hydroxybenzothiophenes having the unusual 2-enamido side chains, such as those of Formula I: ##STR2##
Compounds of formula I have been found to be effective inhibitors of both cyclooxygenase and lipoxygenase and
3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxyphenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and
3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxy-phenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and
3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxy-phenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoes, and 1,2,4-triazoles, and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and
2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now
2-substituted amino-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines as antiinflammatory agents
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 2-substituted amino-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds
Thiadiazole or oxadiazole analogs of fenamic acids containing substituted hydroxamate side chains as antiinflammatory agents
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND OF THE INVENTION
The present invention is a novel compound which is a thiadiazole or oxadiazole analog of a fenamic acid having a substituted hydroxamate side chain and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical compositions and methods of use thereof
Nejúplnější databáze léčivých bylin podložená vědou
- Funguje v 55 jazycích
- Bylinné léky podporované vědou
- Rozpoznávání bylin podle obrázku
- Interaktivní mapa GPS - označte byliny na místě (již brzy)
- Přečtěte si vědecké publikace související s vaším hledáním
- Hledejte léčivé byliny podle jejich účinků
- Uspořádejte své zájmy a držte krok s novinkami, klinickými testy a patenty
Zadejte symptom nebo chorobu a přečtěte si o bylinách, které by vám mohly pomoci, napište bylinu a podívejte se na nemoci a příznaky, proti kterým se používá.
* Všechny informace vycházejí z publikovaného vědeckého výzkumu
