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n acetyl glucosamine/atrofie
Odkaz je uložen do schránky
13 Výsledek
Evaluation of a novel poly N-acetyl glucosamine (pGlcNAc) hydrogel for treatment of the degenerating intervertebral disc.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE
The early stages of degenerative disc disease (DDD) primarily affect the disc nucleus pulposus (NP). Tissue-engineered strategies may enhance intervertebral disc (IVD) functionality. The aim of this study was to develop and evaluate a novel deacetylated poly-N-acetyl glucosamine (pGlcNAc)
Spectropathology-corroborated multimodal quantitative imaging biomarkers for neuroretinal degeneration in diabetic retinopathy.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
UNASSIGNED
Image-based early detection for diabetic retinopathy (DR) needs value addition due to lack of well-defined disease-specific quantitative imaging biomarkers (QIBs) for neuroretinal degeneration and spectropathological information at the systemic level. Retinal neurodegeneration is an early
Characterization of a novel mouse recombinant processing alpha-mannosidase.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
In previous work (Herscovics et al., J. Biol. Chem., 269, 9864-9871), a novel mouse alpha-mannosidase cDNA was isolated by homology, taking advantage of identical regions between the amino acid sequences of the yeast and rabbit liver processing alpha 1,2-mannosidases of different specificities to
Age-related changes of glycosidases in human retinal pigment epithelium.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
This study was undertaken to determine whether there are age-related changes in the specific activities of several glycosidases in fresh retinal pigment epithelial cells (RPE) isolated from the posterior pole of human donor eyes. One hundred and twenty-one pairs of eyes from human donors, between
Oligosaccharide composition is similar in drusen and dense deposits in membranoproliferative glomerulonephritis type II.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Drusen are a feature of age-related macular degeneration (AMD). Lesions similar in appearance to drusen are also found in the fundi of patients with membranoproliferative glomerulonephritis type II (dense deposit disease, DDD). The lamina densa of the glomerular basement membrane, in DDD, is
MRI and localized proton MRS in early infantile form of neuronal ceroid-lipofuscinosis.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
A patient with early infantile neuronal ceroid-lipofuscinosis was examined by magnetic resonance imaging (MRI) and image-guided localized proton MR spectroscopy of brain using short-stimulated echo times. T2-weighted MRI revealed generalized cerebral atrophy and a reduction in signal intensity in
The carbohydrate deposits detected by histochemical methods in the molecular layer of the dentate gyrus in the hippocampal formation of patients with schizophrenia, Down's syndrome and dementia, and aged person.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Post-mortem brain tissue was obtained from 28 patients with brain disorders, of which 15 had clinically diagnosed schizophrenia, 6 Alzheimer type dementia, 5 dementia with tangles and 2 cases of Down's syndrome. The controls were 22 cases from autopsies without brain disorders or with no known
Lectin binding sites in normal and phenobarbitale/halothane treated rat liver. A histochemical study.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The content of carbohydrate residues of both normal and phenobarbitale-halothane-hypoxia exposed rat liver has been examined by means of lectin histochemistry. Eight biotinylated lectins specific to galactose, N-acetyl-galactosamine, N-acetyl-glucosamine, fucose and mannose were applied to paraffin
Echinostoma caproni and E. trivolvis alter the binding of glycoconjugates in the intestinal mucosa of C3H mice as determined by lectin histochemistry.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Mouse (C3H) mucosal glycoconjugates were examined in normal small intestines and intestines infected with Echinostoma caproni or E. trivolvis using six different fluorescein-conjugated lectins: Triticum vulgaris agglutinin (WGA), Ulex europaeus agglutinin I (UEA-I), Ricinus communis agglutinin I
Reactivity of gliadin and lectins with celiac intestinal mucosa.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The binding patterns of gliadin and selected lectins to jejunal biopsy specimens obtained from children with total villous atrophy during active celiac disease (CD; 19 patients) and in remission (16 patients) were examined by light microscopy. Three categories of carbohydrate-specific lectins were
Safety, pharmacokinetics and sialic acid production after oral administration of N-acetylmannosamine (ManNAc) to subjects with GNE myopathy.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
GNE myopathy is a rare, autosomal recessive, inborn error of sialic acid metabolism, caused by mutations in GNE, the gene encoding UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase. The disease manifests as an adult-onset myopathy characterized by progressive skeletal muscle weakness
Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF(165).
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Vascular endothelial growth factor 165 (VEGF165) is an important extracellular protein involved in pathological angiogenesis in diseases such as cancer, wet age-related macular degeneration (wet-AMD) and retinitis pigmentosa. VEGF165 exists in two different isoforms: the angiogenic VEGF165a, and the
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
It has been established for a long time that brain glucose metabolism is impaired in Alzheimer's disease. Recent studies have demonstrated that impaired brain glucose metabolism precedes the appearance of clinical symptoms, implying its active role in the development of Alzheimer's disease. However,
Nejúplnější databáze léčivých bylin podložená vědou
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Zadejte symptom nebo chorobu a přečtěte si o bylinách, které by vám mohly pomoci, napište bylinu a podívejte se na nemoci a příznaky, proti kterým se používá.
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