The TrainToTend online responsible marijuana vendor training teaches responsible sales practices in five modules: Module 1, The Laws; Module 2, ID Checking; Module 3, Health Effects; Module 4, Customer Service, and Module 5, Rules of the Trade. The training content will be conveyed using online educational activities providing application and feedback such as in tabs with appropriate graphics and interactive simulations where users apply the skill and receive informative/corrective feedback.

Usual and customary training in retail sales practices delivered to employees at retail recreational marijuana stores by store managers. Some retail stores in Colorado may receive responsible marijuana vendor training of some type from another state-approved training provider. Thus, we consider the outlets in the control group to have usual and customer sales training but not to be entirely untrained.

Cannabis

Employees at retail recreational marijuana stores assigned to the the responsible marijuana vendor training will register them on TrainToTend online training program, create a user profile, and complete the training within four weeks from initial registration. Personnel who complete the training will receive a certificate of completion. New hires at the stores during the trial will be registered and complete the training within four weeks of commencing work. Separate versions of the training will be available reflecting differences in the laws/regulations on recreational marijuana sales in Colorado, Oregon, and Washington State and the content will be reviewed and approved by state regulators.

Responsible Marijuana Vendor Training

Pacific Institute for Research and Evaluation

Klein Buendel, Inc.

Intervening to Prevent Youth Access to Marijuana Phase II

Successful purchase attempts of a recreational marijuana product by underage-appearing pseudo-patron buyer will be assessed by pseudo-patron teams of a buyer and observer. The observer will enter the retail recreational marijuana store, showing a valid ID indicating they are 21 or older. The buyer will attempt to enter the store. If asked for an ID, the buyer will say they do not have a driver's license (acceptable form of ID) and offer instead a college ID (unacceptable form of ID). If permitted to enter store, buyer will ask to purchase pre-rolled joints. When the clerk asks the buyer to make payment, the buyer will say they do not have enough money and leave the store. The observer and buyer will record the outcome of the purchase attempt. No actual recreational marijuana product will be purchased.

Observers in the pseudo-patron teams will record the presence of signage in the stores required by state regulations.

At the conclusion of the project Klein Buendel Inc. will initiate a data sharing plan to make data from this project publicly available via archive files and publish reports describing study procedures in detail in peer-reviewed academic journals. Public data sets will be de-identified so that they are free of all identifiers that would permit linkages to individual research participants and of variables that could lead to deductive disclosure of the identity of individual participants. Individuals wishing to use this data will be required to fill out the KB Data Sharing Request Form, which asks for information on the type of data being requested, anticipated data use, research questions, study design, variables, analysis plan, and IRB approval.

Participants will be unaware of the psuedo-underage assessment of their retail recreational marijuana store. Pseudo-patron assessment teams will be unaware of the experimental condition to which each retail recreational marijuana store is assigned.

Treatment with naltrexone for two months together with psycho-social support

Alcohol-dependence

Naltrexone

Dept. of Nuclear Medicine, TASMC

The Effects of Treatment With Naltrexone in Alcohol and Cannabis-dependent Patients

Brain Imaging Study on the Effects of Treatment With Naltrexone on Cue-induced Craving and Brain's Metabolic Changes in Alcohol and Cannabis-dependent Patients

Patients will be tested for alcohol at the end of treatment after 2 months

Alcohol and cannabis-dependent patients undergoing treatment with naltrexone will be assessed before and after treatment by the alcohol-cue exposure together with measures of the brain's metabolism using [18F] Fluoro-dioxyglucose (FDG) as the radiotracer in Positron Emission Tomography (PET) and subjective craving responses to the cues.

non-alcoholic fatty liver disease/konopí

Intervening to Prevent Youth Access to Marijuana Phase II

The Effects of Treatment With Naltrexone in Alcohol and Cannabis-dependent Patients

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