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papaverine/hypoxia
Odkaz je uložen do schránky
Strana 1 z 57 Výsledek
Effect of (-)eburnamonine, papaverine and UDP-glucose on cerebral energy state during and after experimental hypoxia and ischaemia in beagle dog.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The effect of (-)eburnamonine, papaverine and UDP-glucose intracarotid perfusion has been evaluated in the brain of beagle dogs during various conditions of cerebral damage (hypoxia, hypoxia plus incomplete ischaemia, hypoxia plus complete ischaemia), and after 3, 15 or 30 min of the post-hypoxic
Effect on ventilation of papaverine administered to the brain stem of the anaesthetized cat.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
1. To investigate whether cerebral vasodilatation by itself contributes to the decrease in ventilation as found during brain stem hypoxia the role of cerebral vasodilatation on minute ventilation was investigated in twelve cats anaesthetized with alpha-chloralose-urethane. 2. Cerebral vasodilatation
Local specificity in responses of canine coronary vessels to oxygen deficiency and antianginal drugs.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Influence of oxygen deficiency and vasodilating drugs on coronary arterial tonus was investigated. In the fibrillating heart, hypoxia initially decreased total coronary resistance, later increased it, and exerted little effect on large coronary arteries. Dilation of helically cut specimens of the
Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE
Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I). We tested the hypothesis that topical pretreatment with the selective potassium channel agonists NS1619 and aprikalim preserves
Anoxia and capillary filtration coefficient in the isolated cat hindlimb.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Isolated cat hindlimbs were perfused from a reservoir with an albumin-blood mixture at a constant flow of 20 ml X min-1 X 100 g muscle-1 while alternately bubbling the perfusate with either 95% O2-5% CO2 gas mixture or a 95% N2-5% CO2 mixture for 50- to 60-min periods. Capillary filtration
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The synaptosomal fraction obtained from the motor area of the cerebral cortex of normocapnic, normoxic or hypoxic "young adult," "mature" and "senescent" beagle dogs is incubated and analyzed for : ATP, ADP, AMP, creatine phosphate, pyruvate and lactate. The data are compared with those obtained
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Synaptosomal preparations from the motor area of the cerebral cortex of normocapnic, normoxic or hypoxic untreated beagle dogs and phenobarbital-, papaverine-, and (-) eburnamonine-treated dogs were incubated for 10 min at 24 degrees C and analyzed for ATP, ADP, AMP creatine phosphate, pyruvate, and
Transport of papaverine in rat kidney cortical slices.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Previous results (J. Pharm. Dyn., 7, 342, 1984) from this laboratory indicated that papaverine, a classical phosphodiesterase inhibitor, inhibited the transport of organic anions such as p-aminohippurate (PAH) and urate in rat kidney cortical slices. The transport of papaverine itself, an organic
Iloprost maintains acetylcholine relaxations of isolated rabbit aortic strips submitted to hypoxia.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The protective activity of iloprost against hypoxia was studied in isolated rabbit aortic strips precontracted with angiotensin II on the relaxant effect of acetylcholine. Exposure of the strips to hypoxia in the medium of Krebs alone for 48 h caused a highly significant decrease in the relaxing
Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The purpose of these experiments was to determine the utility of a new method for monitoring CBF using a venous outflow technique with an extracorporeal circulation and to examine the effects of agents that potentiate or antagonize the actions of adenosine on the blood flow response to brief periods
Effect of intermittent mild hypoxia and drug treatment on synaptosomal nonmitochondrial ATPase activities.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Synaptosomal nonmitochondrial ATPases linked to the energy-utilizing systems were evaluated in cerebral cortex from normoxic rats and rats submitted to mild intermittent normobaric hypoxia [12 hr daily exposure to N2:O2 (90:10) mixture for 4 weeks]. The activities of Na+,K(+)-ATPase; high- and
Modifications by chronic intermittent hypoxia and drug treatment on skeletal muscle metabolism.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The energy metabolism was evaluated in gastrocnemius muscle from 3-month-old rats subjected to either mild or severe 4-week intermittent normobaric hypoxia. Furthermore, 4-week treatment with CNS-acting drugs, namely, alpha-adrenergic (delta-yohimbine), vasodilator (papaverine, pinacidil), or
Hypoxia-induced release of prostaglandins: mechanisms and sources of production in coronary resistance vessels of the isolated rabbit heart.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The mechanism of hypoxia-induced prostacyclin (PGI2) release was studied in isolated, modified Krebs-Henseleit buffer perfused rabbit hearts under constant-flow conditions. The contribution of vascular endothelium and the role of catecholamines and calcium influx through L-type calcium (Ca2+)
Altered hypoxia-induced coronary vasodilatation in diabetic rabbit heart.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The effect of type 1 diabetes mellitus on hypoxia-induced coronary vasodilation was studied in isolated perfused rabbit hearts. Four groups of hearts were compared: control hearts from normal rabbits perfused with physiological buffer (5 mM glucose and 2 mM pyruvate added), hearts from
Coronary reactions to cardiac hyperactivity and to hypoxia in isolated perfused heart of rat.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
1. Continuous recording of cardiac force of contraction, heart rate and coronary flow from isolated perfused hearts of rats was used to study coronary reactions: (a) to cardiostimulation with noradrenaline, CaCl2, or electrically induced tachycardia; (b) to short duration stoppage of coronary inflow
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