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CROSS REFERENCE TO RELATED APPLICATION
The present application is a 35 U.S.C. .sctn.371 National Phase Entry Application from PCT/JP2012/062423, filed May 15, 2012, designating the United States, which in turn claims priority to Japanese Patent Application No. 2011-109599, filed on May 16, 2011,
BACKGROUND OF THE INVENTION
Throughout the application various publications are referenced in parentheses. The disclosures of these publications in their entireties are hereby incorporated by reference in the application in order to more fully describe the state of the art to which this invention
SCOPE OF THE INVENTION
This invention refers to a pharmaceutical composition that comprises the 2,5-dihydroxybenzenesulfonic acid, and its employment in the preparation of a medicine for treatment of diseases characterized by an intense cell proliferation, vascularization (angiodependent diseases)
TECHNICAL FIELD
The present invention relates to methods for early detection of cancer, and for monitoring progression, metastasis, and/or treatment efficacy of cancer. In particular, the invention provides a method for detection of cancer comprising detection of analytes indicative of cancer or a
TECHNICAL FIELD
This invention pertains to a method to target cancer cells that over-express voltage-gated sodium channels (VGSCs or "sodium channels") and to cause osmotic lysis of these cancer cells by initially inhibiting the sodium, potassium-adenosine triphosphatase (Na.sup.+, K.sup.+-ATPase or
This invention relates to compounds which have the ability to block potassium ion channels. In particular, the invention relates to sulphonylurea, sulphonylthiourea and sulphonylguanidine compounds which act to block potassium ion channels regulated by intracellular concentrations of adenosine
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to thienopyridine compounds which are potassium channel inhibitors. Pharmaceutical compositions comprising the compounds and their use in the treatment or prevention of cancer, arrhythmias, autoimmune diseases and
BACKGROUND OF THE INVENTION
Throughout the application various publications are referenced in parentheses. The disclosures of these publications in their entireties are hereby incorporated by reference in the application in order to more fully describe the state of the art to which this invention
FIELD OF THE DISCLOSURE
Compositions and methods are disclosed for treatment of numerous cancers with a halopyruvate. As such, the present invention involves the fields of chemistry, pharmacology, and biology.
BACKGROUND OF THE DISCLOSURE
Perhaps no other word or diagnosis strikes as much fear into
SUMMARY OF THE INVENTION
This invention relates to a method of treating or inhibiting cancer cells in the pancreas, liver, kidney, lymph glands, salivary glands, breast, lung and stomach of humans, by administration of an alkali metal or alkaline earth metal salt of 5,6-O-benzylidene-L-ascorbic
FIELD OF THE INVENTION
The present invention relates to cancer treatment. More particularly, it relates to a method for treating and curing cancer, and to compounds for use in the treatment. The present invention provides a totally new and unique approach to the identification of the primary
BACKGROUND OF THE INVENTION
This invention is in the field of pharmacology, and relates to drugs that are useful for treating cancerous tumors.
The cellular physiology and genetic basis of cancerous tumors are well-known and are discussed in numerous reference works, including DeVita et al 1993,
FIELD OF THE INVENTION
This invention relates to the use of certain bisarylamines as potassium channel openers and to the treatment of diseases modulated by potassium channel opening. Additionally, this invention relates to novel compounds that are useful as potassium channel openers.
BACKGROUND OF
BACKGROUND OF THE INVENTION
Ion channels are cellular proteins that regulate the flow of ions, including calcium, potassium, sodium and chloride, into and out of cells. These channels are present in all human cells and affect such processes as nerve transmission, muscle contraction and cellular
BACKGROUND OF THE INVENTION
Ion channels are cellular proteins that regulate the flow of ions, including calcium, potassium, sodium and chloride, into and out of cells. These channels are present in all human cells and affect such processes as nerve transmission, muscle contraction and cellular