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ribonucleic acid/seizures

Odkaz je uložen do schránky
ČlánkyKlinické testyPatenty
Strana 1 z 38 Výsledek

The effect of convulsions induced by flurothyl on ribonucleic acid synthesis in rat cerebral cortex during the recovery phase.

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The effect of convulsions, induced by flurothyl, on RNA synthesis in purified unfractionated nuclei and the cytoplasm of rat cerebral cortex was studied by using a double-label technique involving injection of [3H]- and [14C]-orotate intracisternally. 2. Intact RNA was extracted in 80% yield by an

Effects of electrically induced convulsions and transmitter substances on ribonucleic acid turnover in brain slices.

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[Ribonucleic acid in the brain of animals during electroconvulsive seizures. (A simple method of cytophotometry)].

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CHANGES IN THE RIBONUCLEIC ACID CONTENT OF THE BRAIN DURING EXPERIMENTALLY INDUCED CONVULSIONS.

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OBJECTIVE Glutamate receptor 6 is strongly implicated in human refractory epilepsy and in kainic acid (KA)-induced status epilepticus (SE). In vitro pharmacologic studies with newer antiepileptic drugs (AEDs) are increasingly indicating the role of glutamate receptor 5 (GluR5) in epilepsy. Glutamate

Adrenal steroids mediate the increase of hippocampal nerve growth factor biosynthesis following bicuculline convulsions.

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Northern blot analysis of nerve growth factor (NGF) messenger ribonucleic acid (mRNA), together with a two-site enzyme immunoassay for NGF protein, showed that a convulsive dose of bicuculline (0.4 mg/kg, IV) induced a rapid (within 1 hour) three-fold increase in hippocampal NGF mRNA. This increase

Mutation analysis of WASF2 and GALE genes in one Chinese family with benign familial infantile convulsions with a novel locus.

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Benign familial infantile convulsions (BFIC) are an autosomal dominant form of idiopathic epilepsy in which partial and generalized seizures commence in the first 3 months of life and spontaneously remit by age 1 year. As it is still unknown whether WASF2 and GALE genes are responsible for pure BFIC

Molecular tools for the characterization of seizure susceptibility in genetic rodent models of epilepsy.

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Epilepsy is a chronic neurological disorder characterized by abnormal neuronal activity that arises from imbalances between excitatory and inhibitory synapses, which are highly correlated to functional and structural changes in specific brain regions. The difference between the normal and the

Overexpression of the immediate-early genes Egr1, Egr2, and Egr3 in two strains of rodents susceptible to audiogenic seizures.

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Genetic animal models of epilepsy are an important tool for further understanding the basic cellular mechanisms underlying epileptogenesis and for developing novel antiepileptic drugs. We conducted a comparative study of gene expression in the inferior colliculus, a nucleus that triggers audiogenic

Pancreatitis-associated protein-I and pancreatitis-associated protein-III expression in a rat model of kainic acid-induced seizure.

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The pancreatitis-associated protein (PAP) family (also known as the regenerating gene (Reg) family) is a group of 16 kDa secretory proteins structurally classified as the calcium dependent-type lectin superfamily. Some PAP family members are expressed in neurons following peripheral nerve injury and
Aminoacyl-transfer ribonucleic acid (RNA) synthetases (ARSs) are a group of enzymes required for the first step of protein translation. Each aminoacyl-transfer RNA synthetase links a specific amino acid to its corresponding transfer RNA component within the cytoplasm, mitochondria, or both.

Increased IL-1beta production from dsRNA-stimulated leukocytes in febrile seizures.

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This study examined the possibility that children with and without a history of febrile seizures might mount different immune responses to double-stranded ribonucleic acid, which is a common viral factor that induces host cell immune responses, and is recognized by Toll-like receptor 3. The

Temporal profile of connexin 43 mRNA expression in a tetanus toxin-induced seizure disorder.

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The messenger ribonucleic acid (mRNA) of gap junction protein connexin 43 was quantified in the tetanus toxin rat model of focal epilepsy following injection of toxin into the left amygdala. Animals were monitored electrographically at weekly intervals with bilateral amygdala electrodes. Cohorts of

Sequence complexity of polyadenylate ribonucleic acid in El mouse brain.

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To elucidate the sequence complexity of polyadenylate messenger RNA [poly(A+)mRNA] regarding the seizure-susceptible El mouse brain, the proportion of complexity was measured by saturation hybridization using a single-copy DNA (scDNA) with excess RNA. At saturation, 3.81, 3.85 and 4.00% of scDNA

Glutamic acid decarboxylase messenger ribonucleic acid is regulated by estradiol and progesterone in the hippocampus.

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Ovarian steroids modulate learning, memory, and epileptic seizure activity, functions that are mediated in part by the hippocampus. Normal function depends on precise interactions between the inhibitory gamma-aminobutyric acid (GABA)ergic and excitatory glutamatergic neurons of the hippocampus. To
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