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sinusitis/phosphatase

Odkaz je uložen do schránky
ČlánkyKlinické testyPatenty
Strana 1 z 29 Výsledek

The expression of cancerous inhibitor protein phosphatase 2A in chronic rhinosinusitis with nasal polyps.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
CONCLUSIONS The study suggests that cancerous inhibitor of protein phosphatase 2A (CIP2A) expression and eosinophilia associate with chronic rhinosinusitis with nasal polyps with aspirin exacerbated respiratory disease (CRSwNP + AERD). Further studies with a larger sample size are needed to evaluate

[Effect of dibunol on the course of experimental sinusitis].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Experimental sinusitis in rabbits was induced by a chemical burn of the mucous membrane. Local application of dibunol decreased the intensity of the purulent inflammation in the sinuses and that of perifocal serous inflammation. Serous inflammation of the contralateral sinus was practically absent.

Interleukin (IL)-13 and IL-17A contribute to neo-osteogenesis in chronic rhinosinusitis by inducing RUNX2.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
There is increasing evidence supporting the impact of neoosteogenesis in the pathophysiology of chronic rhinosinusitis (CRS), especially in the recalcitrant group of patients. Runt-related transcription factor 2 (RUNX2), a member of the RUNX family, controls osteoblast differentiation

MUC4 impairs the anti-inflammatory effects of corticosteroids in patients with chronic rhinosinusitis with nasal polyps.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND Current evidence suggests that membrane-tethered mucins could mediate corticosteroid efficacy, interacting with glucocorticoid receptor (GR) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Mucin 4 (MUC4)-tethered mucin is expressed in nasal polyp (NP) epithelial cells
BACKGROUND The aim of this study was to explore the upregulated nuclear factor kappaB (NF-kappaB)/microRNA-155 (miR-155) in regulating inflammatory responses and relapse of chronic rhinosinusitis (CRS) with nasal polyps (NP), which underlies the molecular mechanism of glucocorticoid treatment.

[Histopathologic study of the ethmoid bone in chronic sinusitis].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE To investigate the histopathologic study of the ethmoid bone in chronic sinusitis (CRS) and the role of bone pathology in the pathogenesis of CRS. METHODS Specimens of mucosa of ethmoid sinus with bone were collected during operation from 40 patients with CRS, 25 males and 15 females, aged

Chronic rhinosinusitis osteoblasts differ in cellular properties from normal bone.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND Osteitis, characterized by bony thickening and remodeling, is often considered a hallmark of recalcitrant rhinosinusitis. However, there is limited literature examining the bone in chronic rhinosinusitis (CRS) pathology. In this study we cultured osteoblasts from bone harvested during
BACKGROUND Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease of the upper airways frequently associated with asthma. Bacterial infection is a feature of CRSwNP that can aggravate the disease and the response to glucocorticoid treatment. OBJECTIVE We examined whether

Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Eosinophilic chronic rhinosinusitis (ECRS), a subgroup of chronic rhinosinusitis with nasal polyps, is recognized as a refractory eosinophilic disorder characterized by both upper and lower airway inflammation. In some severe cases, disease control is poor, likely due to local steroid insensitivity.

Mucin 1 downregulation associates with corticosteroid resistance in chronic rhinosinusitis with nasal polyps.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND A number of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) are resistant to oral corticosteroids. Mucin 1 (MUC1) shows anti-inflammatory properties, and its cytoplasmic tail (CT) interacts with transcription factors, facilitating their nuclear translocation. Because

Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma.

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE To identify genes whose expression is most characteristic of chronic rhinosinusitis and aspirin-sensitive asthma through genome-wide transcriptional profiling of nasal polyp tissue. METHODS Prospective, controlled study conducted at a tertiary care institution. METHODS Thirty genome-wide

Extreme elevations of alkaline phosphatase in pregnancy: A case report

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Background: The normal serum concentration of alkaline phosphatase (ALP) in adults over the age of 18 ranges from 37 to 116 U/L, while in pregnant women levels of up to twice that upper limit can still be normal. There have been very few reports of extreme

[A horse with Cushing's disease].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
A thirteen-year-old Dutch warmblooded mare was referred to the Faculty of Veterinary Medicine because of a sinusitis. She was thin with a potbellied appearance. Her coat was dull with long wavy hair. Unilateral (left) purulent nasal discharge was evident. A cbc revealed leucopenia (3.9 G.L.-1) and

[Retrospective analysis of 273 benign fibro osseous lesionsin the sinus and maxillofacial region].

Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Objective:To compare and analyze the incidence, clinical features ,imaging features, the preoperative serum alkalinosis phosphatase (ALP) and recurrence rates of osteoma, ossifying fibroma (OF), and fibrous dysplasia (FD) in sinus and maxillofacial benign fibrosis (FOLS). Method: The 273 cases of
Avian haemolytic Actinobacillus-like organisms have tentatively been named Bisgaard taxon 26. Phenotypic information has been published on 65 strains of this taxon. In the current study, 31 isolates were selected for genotypic characterization. Thirty strains had the same rpoB sequence and only one
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