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Strana 1 z 18 Výsledek
Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Bluetongue is a severe, economically important disease of ruminants that is widely distributed in tropical and temperate regions around the world. It is associated with major production losses, restrictions of animal movements and trade, as well as costs associated with developing and implementing
Factors associated with hepatitis C viremia in a large cohort of HIV-infected and -uninfected women.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND
Co-infection with hepatitis C virus (HCV) is common among HIV-infected women.
OBJECTIVE
To further our understanding of the risk factors for HCV viremia and the predictors of HCV viral load among women.
METHODS
We investigated sociodemographic, immunologic, and virologic factors
Evaluation of the immunogenicity of a transgenic tobacco plant expressing the recombinant fusion protein of GP5 of porcine reproductive and respiratory syndrome virus and B subunit of Escherichia coli heat-labile enterotoxin in pigs.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Escherichia coli heat-labile enterotoxin B subunit (LTB) can be used as an adjuvant for co-administered antigens. Our previous study showed that the expression of neutralizing epitope GP5 of porcine reproductive and respiratory syndrome virus (PRRSV) in transgenic tobacco plant (GP5-T) could induce
The unique challenges facing HIV-positive patients who smoke cigarettes: HIV viremia, ART adherence, engagement in HIV care, and concurrent substance use.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Evidence suggests that smoking may have negative associations with HIV health outcomes. The smoking rate in our sample of people living with HIV (N = 333) was triple that of the general population (57 v. 19 %). Regression analyses revealed that (smokers v. non-smokers) reported lower medication
Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The effect of genetic polymorphisms for glutathione S-transferase ( GST) M1, GSTT1, GSTP1-1( GSTP1), cytochrome P450 2E1 ( CYP2E1) and aldehyde dehydrogenase 2 ( ALDH2) on the risk of hepatocellular carcinoma (HCC) was observed in 78 Japanese patients with HCC and 138 non-cancer hospital controls.
Hypogonadism in men receiving methadone and buprenorphine maintenance treatment.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The aim of this study was to determine the prevalence and investigate the aetiology of hypogonadism in men on methadone or buprenorphine maintenance treatment (MMT, BMT). 103 men (mean age 37.6 +/- 7.9) on MMT (n = 84) or BMT (n = 19) were evaluated using hormone assays, body mass index (BMI),
Associated actinomycosis and rhinopharyngeal adenocarcinoma during HIV infection: diagnostic and therapeutic issues.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
An extremely infrequent episode of nasopharyngeal actinomycosis associated with squamous adenocarcinoma occurred in an HIV-infected male patient with a previous diagnosis of AIDS, treated with combined antiretroviral therapy taken with insufficient adherence, such that a satisfactory immune system
Impact of Pharmacy Type on HIV Viral Suppression: A Retrospective Cross-Sectional Cohort Study
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Background: People with HIV (PWH) use various pharmacy types beyond traditional local pharmacies. Some specialized pharmacies offer additive adherence services such as refill reminders, expedited delivery, and adherence packaging.
Hepatitis C virus infection is not an independent risk factor for obstructive lung disease.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Several epidemiological studies have suggested that hepatitis C virus (HCV) infection is associated with the presence of obstructive lung disease (OLD). However, there is a strong link between HCV infection and tobacco abuse, a major risk factor for the development of OLD. In this study we analyzed
Impact of HIV on lung tumorigenesis in an animal model.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Many HIV patients on antiretroviral therapy have controlled viremia and restored (albeit partially) immunity. Yet, they have high rates of lung cancer, even after controlling for smoking. We tested the hypothesis that HIV proteins accelerate development/progression of lung cancer in an
Hepatic artery thrombosis after orthotopic liver transplantation: a review of nonsurgical causes.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Hepatic artery thrombosis (HAT) is one of the principal causes of morbidity and graft loss following liver transplantation. There are several risk factors for the development of HAT; technical aspects of the arterial anastomosis are important particularly for early thrombosis, but the improvement of
Group B Streptococcus colonization by HIV status in pregnant women: prevalence and risk factors.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
OBJECTIVE
To examine the prevalence of and risk factors for group B Streptococcus (GBS) colonization in an HIV-infected and uninfected pregnant population.
METHODS
We conducted a retrospective double cohort study comparing the prevalence of GBS colonization between 90 HIV-infected and 1947
Steric accessibility of the cleavage sites dictates the proteolytic vulnerability of the anti-HIV-1 antibodies 2F5, 2G12 and PG9 in plants.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Broadly neutralizing antibodies (bNAbs) to human immunodeficiency virus type 1 (HIV-1) hold great promise for immunoprophylaxis and the suppression of viremia in HIV-positive individuals. Several studies have demonstrated that plants as Nicotiana benthamiana are suitable hosts for the generation of
Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Filovirus infections can cause a severe and often fatal disease in humans and nonhuman primates, including great apes. Here, three anti-Ebola virus mouse/human chimeric mAbs (c13C6, h-13F6, and c6D8) were produced in Chinese hamster ovary and in whole plant (Nicotiana benthamiana) cells. In pilot
Hepatitis B- and hepatitis C-related hepatocellular carcinomas in the United States: similarities and differences.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND
Hepatitis B and Hepatitis C (HBV and HCV) infections are both major causes of hepatocellular carcinoma (HCC). However, HCC caused by each of these two viruses has unique characteristics that should be studied independently to that of another one. While HBV- and HCV-related HCCs share
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