West Nile Fever

VRC-WNVDNA020-00-VP

National Institutes of Health Clinical Center, 9000 Rockville Pike

Phase I Study of West Nile Virus Vaccine

A Phase I Study of the Safety and Immunogenicity of a West Nile Virus Recombinant DNA Plasmid Vaccine, VRC-WNVDNA020-00-VP, in Healthy Adult Subjects

National Institute of Allergy and Infectious Diseases (NIAID)

West Nile Virus

Encephalitis

Myelitis

Natural History of West Nile Virus Infection

Investigation of the Natural History of West Nile Virus Infection in Patients With Recently Acquired West Nile Fever or Neuroinvasive Disease

National Institutes of Health Clinical Center (CC)

20 subjects to receive Polygam® S/D (IVIG).

Omr-IgG-am™ 5% is provided in 100 ml bottles (5.0 grams) as a sterile solution containing 5% protein, 10% maltose and water for injection. This product is licensed in Israel, but not in the US.

Omr-lgG-am

Polygam® S/D is a solvent/detergent treated, sterile, freeze-dried preparation of highly purified immunoglobulin G (IgG) derived from large pools of human plasma. When reconstituted (5%) with the supplied diluent (sterile water for injection, USP) Polygam® S/D contains approximately 50mg of protein per ml (approximately 90% is gamma globulin); 3mg/ml human albumin, 22.5 mg/ml glycine, 20 mg/ml glucose, 2mlg/ml polyethylene glycol (PEG), 1 mcg/ml tri-nbutyl phosphate, 1 mcg/ml octoxynol 9, and 100 mcg/ml polysorbate 80.

Polygam® S/D

Placebo

University of Alabama at Birmingham

University of South Alabama Medical Center

St. Joseph's Hospital and Medical Center

Mayo Clinic Hospital

University of Arizona Health Sciences Center

University of Arkansas

Enloe Medical Center

Seton Medical Center

City of Hope National Medical Center

Kaiser Permanente South Bay Medical Center

University of Southern California

University of California Irvine

University of California Davis Medical Center

University of California San Francisco

California Pacific Medical Center

Santa Rosa Kaiser Medical

Exempla St. Joseph Hospital

University of Colorado

George Washington University Medical Center

Idaho Falls Infectious Diseases, PLLC

Loyola University

Indiana University

University of Kansas Medical Center

Via Christi Regional Medical Center

University of Kentucky

Tulane University

Johns Hopkins University

National Institutes of Health

University of Michigan

Wayne State University

Washington University in St. Louis

Saint Louis University

Mercury Street Medical Group

Infectious Disease Specialists, PC

Central Nebraska Medical Clinic

McCook Clinic, PC

Great Plains Regional Medical Center

VA Medical Center - Omaha

Creighton University

University of Nebraska Medical Center

Clara Maass Medical Center

University of New Mexico

Flushing Hospital Medical Center

St. Alexius Medical Center

Dakota Clinic at Innovis

MeritCare Hospital

Trinity Health - Hospital

University Hospital

University Hospitals of Cleveland

University of Toledo

Wright-Patterson Medical Center

Legacy Good Samaritan

Lehigh Valley Hospital

The Reading Hospital and Medical Center

Memorial Hospital of RI

Rhode Island Hospital

Infectious Disease Consultations - Rapid City

Avera Research Institute

Vanderbilt University

The University of Texas Southwestern Medical Center

The University of Texas Medical Branch

The University of Texas Health Science Center at Houston

The University of Texas Health Science Center

Wilford Hall Medical Center

The University of Texas Health Science Center at Tyler

University of Virginia

University of Calgary

University of Alberta

University of Manitoba

IVIG - West Nile Encephalitis: Safety and Efficacy

A Phase I/II Randomized, Placebo-Controlled Trial to Assess the Safety and Efficacy of Intravenous Immunoglobulin G (OMR-IGG-AM) Containing High Anti-West Nile Virus Antibody Titers in Patients With, or at High Risk for Progression to West Nile Virus (WNV) Encephalitis and/or Myelitis

Robert Johnson

west nile fever

asthenia

west nile fever/asthenia

Phase I Study of West Nile Virus Vaccine

Natural History of West Nile Virus Infection

IVIG - West Nile Encephalitis: Safety and Efficacy

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